altretamine


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altretamine

 [al-tret´ah-mēn]
an antineoplastic agent used in the palliative treatment of ovarian carcinoma. It is structurally related to an alkylating agent but does not act as one; its exact mechanism is unknown. Administered orally.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

altretamine

Hexalen Oncology An alkylating anticancer agent. See Chemotherapy.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

altretamine

An anticancer drug used to treat advanced caner of the ovary.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Other drugs that have Food and Drug Administration approval in the setting of recurrent ovarian cancer include topotecan, liposomal doxorubicin, gemcitabine, bevacizumab, altretamine, carboplatin, cisplatin, cyclophosphamide, and melphalan.
Using DeMAND, the researchers showed that a similar subset of proteins is affected by the unrelated drugs sulfasalazine and altretamine. Altretamine is currently used to treat ovarian cancer, but these results suggest that, like sulfasalazine, it could be used for bowel inflammation or rheumatoid arthritis too.
(103.) Drugs that have reached the market with no listed patents, but only regulatory exclusivity, include: Mefloquine HCl (mefloquine hydrochloride), Clozaril (clozapine), Hexalen (altretamine), Leustatin (cladribine), Trasylol (aprotinin bovine), Sclerosol (talc), and Ellence (epirubicin hydrochloride).
The same study found that most plans covered the following drugs, with median copays ranging from $5-$40: lomustine, thioguanine, bexarotene, erlotinib, exemestane, anastrozole, megestrol acetate, tamoxifen, chlorambucil, procarbazine, altretamine, and others.