altered immune response

altered immune response

A reaction in the immune system caused by an allergen or irritant.
References in periodicals archive ?
A new study, led by investigators from Brigham and Womens Hospital and Boston Childrens Hospital, identifies the species of bacteria in the human infant gut that protect against food allergies, finding changes associated with the development of food allergies and an altered immune response. In preclinical studies in a mouse model of food allergy, the team found that giving an enriched oral formulation of five or six species of bacteria found in the human gut protected against food allergies and reversed established disease by reinforcing tolerance of food allergens.
Summary: TEHRAN (FNA)- A new study identifies the species of bacteria in the human infant gut that protect against food allergies, finding changes associated with the development of food allergies and an altered immune response.
This pro-inflammatory cytokine spillover eventually leads to immuno-compromise and has a significant role in the development of insulin resistance.20 These mechanisms are related to hyperglycaemia and insulinopenia, thereby indirectly causing immune dysfunction by indirectly affecting lymphocyte and macrophage dysfunction.24 The altered immune response in individuals with DM is associated with an increased susceptibility to TB,25 leading to an increasing double burden of these diseases, particularly in endemic countries.
Reactivation of a latent HPV infection may be evoked following topical corticosteroid therapy because of an altered immune response (6, 7).
As author Thomas Viola, RPh, CCP writes, "Oral complications of diabetes mellitus include xerostomia (due to dehydration and reduced secretion of saliva), increased susceptibility to bacterial, viral, and fungal infections (due to altered immune response) and increased incidence and severity of caries; and gingivitis and periodontal disease (due to enhanced inflammatory responses, poor wound healing, and microvascular changes).
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease (CD) is chronic inflammatory bowel disorders in which an altered immune response and environmental triggering factors lead to chronic inflammation of the intestinal tract.
Norwegian scabies may not be associated with pruritus due to an altered immune response in these patients.
In this issue of EHP, researchers report an altered immune response to influenza virus infection in adult mice that had been exposed prenatally to 2,3,7,8-tetrachlordibenzo-p-dioxin (TCDD), revealing a novel cellular target of developmental exposures.
In contrast to most viral infections where T cells are considered a normal part of the body's protective response, many scientists in the dengue field have theorized that T cells raised against an individual's first dengue infection dominate the body's immune reaction upon infection with a second dengue strain and mount an altered immune response.
Unfortunately, diabetics often have an altered immune response which makes them much more susceptible to gum disease, but taking PerioBalance may well bring about a reduction in the inflammation and bleeding gums associated with this - and that goes for everybody suffering from gingivitis not just diabetics.
The new study hints that an altered immune response may play a key role.
One consequence of trauma is altered immune response, resulting in an inability to fight infection.