alprostadil


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Related to alprostadil: papaverine

alprostadil

 [al-pros´tah-dil]
name for prostaglandin E1 when used pharmaceutically as a vasodilator and platelet aggregation inhibitor; used for treatment of patent ductus arteriosus and for diagnosis and treatment of impotence.

al·pros·ta·dil

(al-pros'tă-dil),
A vasodilator used for palliative therapy to maintain patency of the ductus arteriosus in neonates with congenital heart defects temporarily.
Synonym(s): prostaglandin E1

alprostadil

/al·pros·ta·dil/ (al-pros´tah-dil) name for prostaglandin E when used pharmaceutically as a vasodilator and platelet aggregation inhibitor; used for the treatment of patent ductus arteriosus and the diagnosis and treatment of impotence.

alprostadil

(ăl-prŏs′tə-dĭl)
n.
A prostaglandin drug, C20H34O5, that acts as a vasodilator and is used in suppository or injectable form to treat erectile dysfunction.

alprostadil

a proprietary form of prostaglandin E1 used to treat impotence and (temporarily) to maintain the patency of the ductus arteriosus in certain neonates.
indication It is recommended as palliative therapy for neonates awaiting surgery to correct congenital cardiac anomalies, such as tetralogy of Fallot and tricuspid atresia.
contraindications It is contraindicated in respiratory distress syndrome and in cases of known hypersensitivity. This drug is contraindicated in pregnant patients.
adverse effects The most common adverse effects are apnea, fever, seizures, cerebral bleeding, flushing, bradycardia, and hypertension.

alprostadil

Urology A formulation of PGE-1 which relaxes the corpus cavernosum, allowing engorging during erection. See Erectile dysfunction, Orgasm.

alprostadil

A PROSTAGLANDIN drug used by penile injection for the treatment of impotence. An erection lasting for two or three hours is commonly achieved, but sales of alprostadil may be adversely affected by the development of drugs such as VIAGRA. Brand names are Caverject, Muse, and Viridal Duo.

Alprostadil

A smooth muscle relaxant sometimes injected into the penis or applied to the urethral opening to treat impotence.
Mentioned in: Impotence

al·pros·ta·dil

(al-pros'tă-dil)
A vasodilator used for palliative therapy to maintain patency of the ductus arteriosus in neonates with congenital heart defects temporarily.
Synonym(s): prostaglandin E1.

alprostadil (alpros´tədil´),

n brand name: Caverject;
drug class: naturally occurring prostaglandin;
action: induces erection by relaxation of trabecular smooth muscle and by dilation of cavernosal arteries;
uses: treatment of erectile dysfunction caused by neurogenic, vasculogenic, psychogenetic, or mixed etiology.
References in periodicals archive ?
Both doses of alprostadil were associated with a significant vasodilatory response.
Both alprostadil groups reported significantly higher levels of sexual arousal and lubrication than the placebo group.
Vitaros, which also combines alprostadil with NexACT technology, has already been approved in Canada to treat erectile dysfunction.
rights for its topical alprostadil erectile dysfunction treatment to partner, Warner Chilcott Company, Inc.
In November 2007, NexMed's New Drug Application for its alprostadil treatment for erectile dysfunction was accepted for review by the FDA and the Company signed a U.
Nasdaq: NEXM), a developer of innovative transdermal products based on its proprietary NexACT([R]) drug delivery technology, today announced that it filed the New Drug Submission (NDS) for its topical alprostadil treatment for erectile dysfunction with Health Canada on October 19, 2007.
The Company is also developing Femprox[R], a topical formulation that incorporates alprostadil with the NexACT[TM] technology for the treatment of Female Sexual Arousal Disorder.
The Company is also developing Femprox(R), a topical formulation that incorporates alprostadil with the NexACT(TM) technology for the treatment of Female Sexual Arousal Disorder.
Alprostadil is a hormone-like substance that is commonly found in the body, and has been used for years to treat male sexual dysfunction.
Current prescription drugs under development include topical alprostadil, many delivery systems for testosterone and intranasal melanocortin analog.