alphaviruses

alphaviruses

A group of 26 viruses transmitted by mosquitoes, eight of which can cause illness, sometimes serious. Alphavirus infections feature fever, muscle and joint pain, a rash and sometimes ENCEPHALITIS. Most cases are mild.
References in periodicals archive ?
The virus is a member of the genus Alphavirus; many alphaviruses are important human pathogens (3, 4).
* Viral polyarthritis is caused by rubella, parvovirus B19 (4), alphaviruses, and hepatitis B.
Alphaviruses having single-stranded RNA genome belong to Togaviridae family of viruses and are divided into arthritogenic viruses (old world) and encephalitogenic viruses (new world) including equine encephalitis viruses.
(2) Similar to other alphaviruses, MAYV RNA has a stop codon at the end of nsP3 gene, and at a low frequency (5-20%), a read-through translation can occur, resulting in nsP1-4 product (Fig.
This could be due to cross-reactivity with other alphaviruses. However, there is currently no evidence of other alphaviruses circulating in Nicaragua.
(34) Alphaviruses are another group of positive-sense RNA viruses transmitted through the bite of an infected mosquito and are a member of the Togaviridae family.
In a sensitivity test involving all chikungunya serotypes and various alphaviruses, flaviviruses, and one phlebovirus, the RT-RPA assay identified all virus genotypes, with the only cross-reaction occurring with O'nyong'nyong virus.
They address genome structure and replication, laboratory diagnosis and detection, interaction with the interferon system, antiviral responses in mosquitoes, animal models of alphavirus-induced inflammatory disease, clinical manifestations of arthritogenic alphaviruses, encephalitic alphaviruses, the application of alphaviruses for gene therapy, and chikungunya virus pathogenesis and the development of control strategies.