protease(redirected from alpha1-protease inhibitor)
Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to alpha1-protease inhibitor: antitrypsin
any peptidase that catalyzes the cleavage of internal bonds in a polypeptide or protein. Inhibition of the action of endopeptidases (proteases) in viruses causes formation of noninfectious particles; certain antiviral drugs work in this way (see protease inhibitors). Called also protease and proteinase.
Descriptive term for proteolytic enzymes, both endopeptidases and exopeptidases; enzymes that hydrolyze (break) polypeptide chains.
protease/pro·te·ase/ (pro´te-ās) endopeptidase.
Any of various enzymes, including the endopeptidases and exopeptidases, that catalyze the hydrolytic breakdown of proteins. Also called peptidase.
an enzyme that is a catalyst in the breakdown of peptide bonds that join the amino acids in a protein. See also proteolysis.
Descriptive term for proteolytic enzymes, both endopeptidases and exopeptidases; enzymes that hydrolyze (i.e., break) polypeptide chains.
proteaseOne of a range of protein-splitting enzymes. One focus of current interest in proteases is in their role in breaking down tissue barriers in the spread of cancer. High concentrations of the activator of one of these proteases has been found to be associated with a poor outlook in cancers of the colon and rectum.
proteaseany enzyme that splits proteins, such as PEPSIN, TRYPSIN, EREPSIN or RENNIN.
protease; proteinase enzyme that breaks down/proteolyses protein
any proteolytic enzyme.
thought to play a part in the pathogenesis of emphysema by permitting excessive proteolysis, especially of elastin.
originate from the pancreas and include trypsin, chymotrypsin and carboxypeptidases. Proteolytic activity of the feces may be evaluated by tests that measure digestion of gelatin or casein-based substrates.