alpha1-antitrypsin deficiency panniculitis

α1-an·ti·tryp·sin de·fi·cien·cy pan·nic·u·li·tis

multiple painful subcutaneous nodules occurring in patients with severe antitrypsin deficiency; biopsies show lobular panniculitis with neutrophils and foamy histiocytes. Some patients formerly diagnosed with Weber-Christian disease show this deficiency.
References in periodicals archive ?
Alpha1-antitrypsin deficiency panniculitis: a histopathologic and immunopathologic study of four cases.