alpha-methylacyl-CoA racemase


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AMACR

Alpha-Methylacyl coenzyme A racemase. An enzyme involved in beta-oxidation of branched-chain fatty acids, the gene for which is overexpressed in certain cancers, in particular prostate.

alpha-methylacyl-CoA racemase

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AMACR

An antibody that is primarily used in histopathology to stain tissues suspected of representing carcinoma of the prostate gland. Its presence substantiates the diagnosis. AMACR is also present in some colonic and some kidney cancer specimens.
References in periodicals archive ?
Immunohistochemical stains for p63 and alpha-methylacyl-CoA racemase, versus a cocktail comprising both, in the diagnosis of prostatic carcinoma: a comparison of the immunohistochemical staining of 430 foci in radical prostatectomy and needle biopsy tissues.
Alpha-methylacyl-CoA racemase as a marker in the differential diagnosis of metanephric adenoma.
The oncocytoma part showed diffuse positivity for E-cadherin and weak positivity for CD117, whereas it was negative for vimentin and alpha-methylacyl-CoA racemase (AMACR).