alpha-lipoic acid


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alpha-lipoic acid

A naturally occurring compound synthesised in small amounts by humans, which is regarded by some authors as a conditionally essential nutrient. It is an antioxidant and may have several roles in the body, such as the chelation of metals (cadmium, copper, iron, lead, mercury and others) and extraction of energy from food. Alpha-lipoic acid is said be effective in treating cardiovascular disease, diabetes mellitus (by preventing glycation), strokes, gangrene, Alzheimer’s disease, Parkinson’s disease and retinal degeneration.
 
The body of peer-reviewed data is limited, but suggests that intravenous lipoic acid may improve peripheral neuropathy in diabetics.

alpha-lipoic acid

C8H14O2S2, a natural coenzyme and antioxidant, used for short-term treatment of peripheral neuropathies.
CAS # 1200-22-2
See also: acid
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References in periodicals archive ?
The Effect of Alpha-Lipoic Acid on Mitochondrial Superoxide and Glucocorticoid-Induced Hypertension.
Cellular and Mitochondrial Support in the Fatigued Patient
Alpha-lipoic acid regulates heme oxygenase gene expression and nuclear Nrf2 activation as a mechanism of protection against arsenic exposure in HepG2 cells.
[alpha]-Lipoic acid mitigates arsenic-induced hematological abnormalities in adult male rats
Comparison of the effect of alpha-lipoic acid and alphatocopherol supplementation on measures of oxidative stress.
Effects of dietary L-carnosine and alpha-lipoic acid on growth performance, blood thyroid hormones and lipid profiles in finishing pigs
Therefore, the aim of our study was to investigate the effect of Alpha-lipoic acid on endothelial dysfunction in youth with type 1 diabetes.
Alpha-lipoic acid and antioxidant diet help to improve endothelial dysfunction in adolescents with type 1 diabetes: A pilot trial
Morley, "Effect of alpha-lipoic acid on memory, oxidation, and lifespan in SAMP8 mice," Journal of Alzheimer's Disease, vol.
[alpha]-lipoic acid inhibits Helicobacter pylori-induced oncogene expression and hyperproliferation by suppressing the activation of NADPH oxidase in gastric epithelial cells
Burning mouth syndrome: open trial of psychotherapy alone, medication with alpha-lipoic acid (thioctic acid), and combination therapy.
Burning mouth syndrome: a perspective
The critical job of alpha-lipoic acid in brain cells is to stand guard over the mitochondrial energy plants, protecting them against damage from the continual onslaught of free radical chemicals.
Outsmarting Alzheimer's: three ways science says you can keep your wits about you
Plasma kinetics, metabolism, and urinary excretion of alpha-lipoic acid following oral administration in healthy volunteers.
A call to reduce the incidence of Alzheimer's disease
Studies show that topical application of alpha-lipoic acid provides antioxidant and anti-inflammatory protection that can improve the appearance of aging skin damaged by exposure to the sun.
Can nutrient-laced cosmetics help you conquer aging skin? EN's 7 tips
The antioxidant alpha-lipoic acid is a common German treatment for diabetic neuropathy; antioxidants protect our bodies from cell-damaging, free radicals.
Approaches to diabetes (part 1)
`Take a daily antioxidant supplement with added zinc and alpha-lipoic acid (which protects liver membranes) - try Solgar Sulphur Antioxidant Complex (pounds 15.75).
Minute Masterclass: Daniela Turley
Specifically, alpha-lipoic acid, vitamin C and trivalent chromium (as in the form chromium picolinate) are thought to be preventative.
Battling blood sugar: environment and diet are factors in rising adult-onset diabetes. (Your Health)

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