alpha-lipoic acid


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alpha-lipoic acid

A naturally occurring compound synthesised in small amounts by humans, which is regarded by some authors as a conditionally essential nutrient. It is an antioxidant and may have several roles in the body, such as the chelation of metals (cadmium, copper, iron, lead, mercury and others) and extraction of energy from food. Alpha-lipoic acid is said be effective in treating cardiovascular disease, diabetes mellitus (by preventing glycation), strokes, gangrene, Alzheimer’s disease, Parkinson’s disease and retinal degeneration.
 
The body of peer-reviewed data is limited, but suggests that intravenous lipoic acid may improve peripheral neuropathy in diabetics.

alpha-lipoic acid

C8H14O2S2, a natural coenzyme and antioxidant, used for short-term treatment of peripheral neuropathies.
CAS # 1200-22-2
See also: acid
References in periodicals archive ?
The Effect of Alpha-Lipoic Acid on Mitochondrial Superoxide and Glucocorticoid-Induced Hypertension.
Alpha-lipoic acid regulates heme oxygenase gene expression and nuclear Nrf2 activation as a mechanism of protection against arsenic exposure in HepG2 cells.
Comparison of the effect of alpha-lipoic acid and alphatocopherol supplementation on measures of oxidative stress.
Therefore, the aim of our study was to investigate the effect of Alpha-lipoic acid on endothelial dysfunction in youth with type 1 diabetes.
Morley, "Effect of alpha-lipoic acid on memory, oxidation, and lifespan in SAMP8 mice," Journal of Alzheimer's Disease, vol.
Burning mouth syndrome: open trial of psychotherapy alone, medication with alpha-lipoic acid (thioctic acid), and combination therapy.
The critical job of alpha-lipoic acid in brain cells is to stand guard over the mitochondrial energy plants, protecting them against damage from the continual onslaught of free radical chemicals.
Plasma kinetics, metabolism, and urinary excretion of alpha-lipoic acid following oral administration in healthy volunteers.
Studies show that topical application of alpha-lipoic acid provides antioxidant and anti-inflammatory protection that can improve the appearance of aging skin damaged by exposure to the sun.
The antioxidant alpha-lipoic acid is a common German treatment for diabetic neuropathy; antioxidants protect our bodies from cell-damaging, free radicals.
`Take a daily antioxidant supplement with added zinc and alpha-lipoic acid (which protects liver membranes) - try Solgar Sulphur Antioxidant Complex (pounds 15.75).
Specifically, alpha-lipoic acid, vitamin C and trivalent chromium (as in the form chromium picolinate) are thought to be preventative.