Alpha-ketoglutarate dehydrogenase complex | definition of alpha-ketoglutarate dehydrogenase complex by Medical dictionary
alpha-ketoglutarate dehydrogenase (redirected from alpha-ketoglutarate dehydrogenase complex)
an enzyme that catalyzes the oxidative decarboxylation of 2-ketoglutaric acid to succinyldihydrolipoate; the succinyl group is later transferred to CoA and the reduced lipoate is oxidized by NAD+; a complex that is a part of the tricarboxylic acid cycle.
References in periodicals archive
Scarpa, "Independent modulation of the activity of alpha-ketoglutarate dehydrogenase complex
by [Ca.sup.2+] and [Mg.sup.2+]," Biochemistry, vol.