alpha-ketoglutarate dehydrogenase

(redirected from alpha-ketoglutarate dehydrogenase complex)

α-ke·to·glu·tar·ate de·hy·dro·gen·ase

an enzyme that catalyzes the oxidative decarboxylation of 2-ketoglutaric acid to succinyldihydrolipoate; the succinyl group is later transferred to CoA and the reduced lipoate is oxidized by NAD+; a complex that is a part of the tricarboxylic acid cycle.
References in periodicals archive ?
Scarpa, "Independent modulation of the activity of alpha-ketoglutarate dehydrogenase complex by [Ca.sup.2+] and [Mg.sup.2+]," Biochemistry, vol.
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