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A highly toxic, heat-stable bicyclic oligopeptide in the mushroom Amanita phalloides. It inhibits transcription by certain RNA polymerases.
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References in periodicals archive ?
Determination of alpha-amanitin in serum and liver by multistage linear ion trap mass spectrometry.
Doctors called a mycologist who questioned the patient and identified the mushroom as the aptly named "death angel," or Amanita bisporigera, which contains the heat-stable toxin alpha-amanitin capable of destroying the liver.
Particularly attractive agents are those that take many days to cause illness, such as the mushroom toxin alpha-amanitin: the lag between eating and illness "could minimize opportunity for public health intervention," as the FDA delicately puts it.