alpha-2 adrenergic receptor agonist

Alpha-2 agonist (alpha-2 adrenergic receptor agonist)

A class of drugs that bind to and stimulate alpha-2 adrenergic receptors, causing responses similar to those of adrenaline and noradrenaline. They inhibit aqueous humor production and a have a wide variety of effects, including dry mouth, fatigue, and drowsiness.
Mentioned in: Glaucoma
References in periodicals archive ?
Dexmedetomidine is an alpha-2 adrenergic receptor agonist (A2ARA) used for sedation and analgesia, and as an adjunct in anesthesia to reduce anesthetic requirements in procedures requiring total intravenous anesthesia (TIVA) (1,2,3).
The alpha-2 adrenergic receptor agonist guanfacine (Tenex) also seems, on the basis of clinical experience and limited research, to have some value for hyperactivity, Dr.
In experiments carried out in heroin-(11) and cocaine-trained rats (12) and rats trained with a heroin-cocaine mixture (13), we found that pharmacological inhibition of NE cell firing and release (by systemic injections of alpha-2 adrenergic receptor agonists at doses that suppress NE cell firing through auto-inhibition), strongly attenuated footshock-induced relapse.

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