ADRA1B

(redirected from alpha-1B adrenergic receptor)

ADRA1B

A gene on chromosome 5q33.3 that encodes alpha-1B-adrenergic receptor, a member of the G protein-coupled receptor superfamily, which activates a phosphatidylinositol-calcium second messenger system, triggering mitogenic responses and regulating growth, proliferation and signalling through the Gq/11 family of G proteins.

Molecular pathology
ADRA1B has been identified as a proto-oncogene.
References in periodicals archive ?
Gene ADRA1B encodes alpha-1B adrenergic receptor ([alpha]1B ADR) that is a member of the G-protein-coupled family of transmembrane receptors (Allen et al.
A behavioral study of alpha-1b adrenergic receptor knockout mice: increased reaction to novelty and selectively reduced learning capacities.
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