Alpha-1B adrenergic receptor | definition of alpha-1B adrenergic receptor by Medical dictionary
ADRA1B (redirected from alpha-1B adrenergic receptor)
ADRA1B A gene on chromosome 5q33.3 that encodes alpha-1B-adrenergic receptor, a member of the G protein-coupled receptor superfamily, which activates a phosphatidylinositol-calcium second messenger system, triggering mitogenic responses and regulating growth, proliferation and signalling through the Gq/11 family of G proteins.
ADRA1B has been identified as a proto-oncogene.
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References in periodicals archive
Gene ADRA1B encodes alpha-1B adrenergic receptor
([alpha]1B ADR) that is a member of the G-protein-coupled family of transmembrane receptors (Allen et al., 1991), located at chromosome 13 in chickens (Gene ID: 373890).
A behavioral study of alpha-1b adrenergic receptor
knockout mice: increased reaction to novelty and selectively reduced learning capacities.