ADRA1A

(redirected from alpha-1A adrenergic receptor)

ADRA1A

A gene on chromosome 8p21.2 that encodes alpha-1A-adrenergic receptor, a member of the G protein-coupled receptor superfamily, which activates a phosphatidylinositol-calcium second messenger system, triggering mitogenic responses and regulating growth, proliferation and signalling through the Gq/11 family of G proteins. ADRA1A is also an older gene name for what is formally known as ADRA1D, see there.
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10:40 ALPHA-1A ADRENERGIC RECEPTOR ACTIVATION ENHANCES NEUROGENESIS
Synaptic has been issued United States patents covering the alpha-1a adrenergic receptor and the use of selective alpha-1a antagonists for the treatment of benign prostatic hypertrophy.
Recent studies have suggested that alpha-1A adrenergic receptors ([alpha]1A-ARs) may regulate neurogenesis and neuronal differentiation (1, 2).
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