alpha subunit

first-named chain (or subunit) occurring in the functional organization of macromolecules, usually proteins, containing two or more chains.

References in periodicals archive ?

About Dupilumab (REGN668/SAR231893) Dupilumab is a fully human investigational monoclonal antibody delivered by subcutaneous injection that targets the alpha subunit of the interleukin 4 receptor (IL-4R alpha).

Sanofi and Regeneron's Dupilumab Named "Clinical Advance of the Year" by Scrip Intelligence

When a bitter compound binds to a bitter taste receptor, the receptor releases a G-protein, which then splits into two parts: a G alpha subunit and G beta-gamma dimer.

Bitter tasting food may help prevent asthma attacks

Through the sequence display method, all the exons of the SCNN1A gene which codes the alpha subunit of epithelial sodium channels were displayed.

Evaluation of gene SCNN1A responsible for the synthesis of alpha subunit of epithelial sodium channel in transient tachypnea of newborn/Yenidoganin gecici takipnesinde epiteliyal sodyum kanali alfa alt biriminin sentezinden sorumlu SCNN1A geninin degerlendirilmesi

We have identified a small molecule, guanabenz, which binds to a regulatory subunit of protein phosphatase 1, PPP1R15A/GADD34, selectively disrupting the stress-induced dephosphorylation of the alpha subunit of translation initiation factor 2 (eIF2 alpha).

United Kingdom - Protein Misfolding: Prion-like Propagation and Cure. Implications for Neurodegenerative Diseases

02), IGF-1:150 ng/ml (140-405), SHBG: 202 mmoI/l (30-100), TSH alpha subunit level: 1.

Three cases with inappropriate TSH syndrome: uygunsuz TSH sendromlu Uc olgu

There are two known alpha subunit isoforms (alpha-1 and alpha-2, Stapleton et al.

Effect of 24 h fasting on gene expression of AMPK, appetite regulation peptides and lipometabolism related factors in the hypothalamus of broiler chicks

Sequence and functional expression of a single alpha subunit of an insect nicotinic acetylcholine receptor.

cDNA cloning and expression analysis of the nicotinic acetylcholine receptor alpha6 subunit in the oriental fruit fly, Bactrocera dorsalis (diptera: tephritidae)

Based on the results of our study, essential erythroid proteins (ankyrin recurrent and FYVE bundle containing protein 1, spectrin alpha, actin-depolymerization factor, actin-depolymerizing factor, LIM bundle and actin binding subunit 1 isoform a, LIM bundle and actin binding subunit 1 isoform b, NADP-dependent malic enzyme, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, mitochondrial NADP (+) dependent malic enzyme 3, ribulose bisphosphate-carboxylase large chain, maturase K) and the required ATP bioenergy (ATP synthase, ATP synthase beta subunit, ATP synthase alpha subunit, ATP-binding protein C12, TP synthase H+ transporter protein, ADF, and alpha-1,2-glycosyltransferase ALG10-A) are included in the protein library of Ankaferd.

Functional proteomic analysis of Ankaferd[R] Blood Stopper / Kanama durdurucu Ankaferd[R] ve etki mekanizmasinin proteomik analizi

Further analysis of mercury's role in influencing the alpha subunit levels in these molecules will be an added help to explain the role of mercury in CNS toxicopathogenesis.

Effects of exposure to low concentrations of nercury on Glycine Alpha-3,-6 GABA-A Chloride and glutamate-gated channel receptors in the HepG2 cell line in culture

today announced that dosing of patients has begun in the first Phase 1 clinical trial of CAM-3001, a fully human monoclonal antibody (MAb) targeting the alpha subunit of the granulocyte-macrophage colony stimulating factor receptor (GM-CSFR).

MedImmune Initiates First Clinical Trial of Monoclonal Antibody Targeting GM-CSFR in Patients with Rheumatoid Arthritis

Human brain nascent polypeptide-associated complex alpha subunit is decreased in patients with Alzheimer's disease and Down syndrome.

Molecular mechanisms of West Nile virus pathogenesis in brain cells

Mutually exclusive exon splicing of type III brain sodium channel alpha subunit RNA generates developmentally regulated isoforms in rat brain.

Developmental neurotoxicity of pyrethroid insecticides: critical review and future research needs