alpha subunit

first-named chain (or subunit) occurring in the functional organization of macromolecules, usually proteins, containing two or more chains.

References in periodicals archive ?

MADD may be caused by mutations in the electron transfer flavoprotein alpha subunit (ETFA), [4] electron transfer flavoprotein beta subunit (ETFB), or electron transfer flavoprotein dehydrogenase (ETFDH) genes.

A Term Newborn with Respiratory Distress, Acidosis, and Hypoglycemia

q] class is one subfamily of the G protein alpha subunit family and is comprised of four genes: G-protein subunit Galphaq (GNAQ), GNA11, GNA14, and GNA15 (Davignon et al.

Molecular cloning, mRNA expression, and localization of the G-protein subunit Galphaq in sheep testis and Epididymis

PDK1, a protein kinase that phosphorylates and thus inactivates pyruvate dehydrogenase alpha subunit, was more than 2-fold over expressed in frataxin knockdown cells.

Down-regulation of bioenergetics in a cellular model of Friedreich Ataxia

McCune-Albright Syndrome is a rare syndrome characterized with excessive function of peripheral endocrine organs and activating mutations of the stimulatory G protein alpha subunit are involved in the pathogenesis.

McCune Albright syndrome in association with excessive GH secretion: case report

Dupilumab is an investigational fully human monoclonal antibody that addresses a novel target: It is directed against the interleukin-4 receptor alpha subunit (IL-4Ra).

Dupilumab advances for severe atopic dermatitis

On the origin of Metazoan adhesion receptors: cloning of integrin alpha subunit from the sponge Geodia cydonium.

Integrins of the starlet sea anemone Nematostella vectensis

For the minority of cases of atopic dermatitis that are more severe--and refractory to topical therapies--new agents in clinical trials include the oral phosphodiesterase-4 inhibitor apremilast and dupilumab, a monoclonal antibody that binds to the alpha subunit of the interleukin-4 receptor.

Novel eczema therapies offer options

Patients of molar pregnancy have high serum levels of Human Chorionic Gonadotropin (hCG), which consists of alpha and beta subunits alpha subunit is identical to TSH and beta subunit has structure to TSH.

Anesthetic Management of Gestational Trophoblastic Disease with Hyperthyroidism

When a bitter compound binds to a bitter taste receptor, the receptor releases a G-protein, which then splits into two parts: a G alpha subunit and G beta-gamma dimer.

Bitter tasting food may help prevent asthma attacks

We have identified a small molecule, guanabenz, which binds to a regulatory subunit of protein phosphatase 1, PPP1R15A/GADD34, selectively disrupting the stress-induced dephosphorylation of the alpha subunit of translation initiation factor 2 (eIF2 alpha).

United Kingdom - Protein Misfolding: Prion-like Propagation and Cure. Implications for Neurodegenerative Diseases

02), IGF-1:150 ng/ml (140-405), SHBG: 202 mmoI/l (30-100), TSH alpha subunit level: 1.

Three cases with inappropriate TSH syndrome: uygunsuz TSH sendromlu Uc olgu

Sequence and functional expression of a single alpha subunit of an insect nicotinic acetylcholine receptor.

cDNA cloning and expression analysis of the nicotinic acetylcholine receptor alpha6 subunit in the oriental fruit fly, Bactrocera dorsalis (diptera: tephritidae)