In January 2012, ANMAT (the agency responsible for the national regulation of drugs, foods and medical technology in Argentina) approved the product for treatment of hepatitis C, multiple sclerosis and cancers in patients whose treatment with recombinant
alpha interferon fails or who become intolerant to treatment with recombinant
alpha interferon as a result of the appearance of neutralizing antibodies.
Although typical chronic viruses are sensitive to and inhibited by
alpha interferon, transmitted HIV-1 viruses grew well in the presence of interferon.
Cummins's work with natural
alpha interferon at low doses, and W.
Multiferon differs from single-subtype recombinant
alpha interferon drug products in that it contains a unique mixture of multiple subtypes of human interferon (a1, a2, a8, a10, a14, a21).
Studies suggest that monotherapy with
alpha interferon is better tolerated and may lead to better sustained virologic response in children than in adults.
The scientists plan to introduce the gene encoding human
alpha interferon into Brassica, an edible crop plant, using a novel and proprietary gene transfer method.
Select patients newly diagnosed with chronic myelogenous leukemia may be able to undergo a course of
alpha interferon treatment that enables them to safely delay and even avoid allogeneic stem cell transplantation and its related mortality risks, Dr.
NEW YORK - The use of
alpha interferon has long been associated with depression, but for the first time, patients enrolled in a clinical trial using
alpha interferon to treat hepatitis C developed psychosis, Dr.
Headquartered in Cambridge, MA, the company's revenues are generated from worldwide sales of AVONEX[registered] (Interferon beta-1a) for treatment of relapsing forms of multiple sclerosis, and from the worldwide sales by licensees of a number of products, including
alpha interferon and hepatitis B vaccines and diagnostic products.
Hepatitis C has no cure and no vaccine to combat it, but a new product, Rebetron, received FDA approval last June for the treatment of chronic hepatitis C in patients who have undergone a relapse following
alpha interferon therapy.
Schering-Plough Corporation, Madison, NJ, announced the US Food and Drug Administration (FDA) has approved Rebetron Combination Therapy containing Rebetol (ribavirin, USP) capsules and Intron A (interferon alfa-2b, recombinant) injection for the treatment of hepatitis C in patients with compensated liver disease previously untreated with
alpha interferon therapy.
Paty had done similar MRI studies of people in clinical trials of
alpha interferon and cyclosporine several years earlier.
