In January 2012, ANMAT (the agency responsible for the national regulation of drugs, foods and medical technology in Argentina) approved the product for treatment of hepatitis C, multiple sclerosis and cancers in patients whose treatment with recombinant alpha interferon
fails or who become intolerant to treatment with recombinant alpha interferon
as a result of the appearance of neutralizing antibodies.
Although typical chronic viruses are sensitive to and inhibited by alpha interferon
, transmitted HIV-1 viruses grew well in the presence of interferon.
Cummins's work with natural alpha interferon
at low doses, and W.
Multiferon differs from single-subtype recombinant alpha interferon
drug products in that it contains a unique mixture of multiple subtypes of human interferon (a1, a2, a8, a10, a14, a21).
Studies suggest that monotherapy with alpha interferon
is better tolerated and may lead to better sustained virologic response in children than in adults.
The scientists plan to introduce the gene encoding human alpha interferon
into Brassica, an edible crop plant, using a novel and proprietary gene transfer method.
Select patients newly diagnosed with chronic myelogenous leukemia may be able to undergo a course of alpha interferon
treatment that enables them to safely delay and even avoid allogeneic stem cell transplantation and its related mortality risks, Dr.
NEW YORK - The use of alpha interferon
has long been associated with depression, but for the first time, patients enrolled in a clinical trial using alpha interferon
to treat hepatitis C developed psychosis, Dr.
Headquartered in Cambridge, MA, the company's revenues are generated from worldwide sales of AVONEX[registered] (Interferon beta-1a) for treatment of relapsing forms of multiple sclerosis, and from the worldwide sales by licensees of a number of products, including alpha interferon
and hepatitis B vaccines and diagnostic products.
Hepatitis C has no cure and no vaccine to combat it, but a new product, Rebetron, received FDA approval last June for the treatment of chronic hepatitis C in patients who have undergone a relapse following alpha interferon
Schering-Plough Corporation, Madison, NJ, announced the US Food and Drug Administration (FDA) has approved Rebetron Combination Therapy containing Rebetol (ribavirin, USP) capsules and Intron A (interferon alfa-2b, recombinant) injection for the treatment of hepatitis C in patients with compensated liver disease previously untreated with alpha interferon
Paty had done similar MRI studies of people in clinical trials of alpha interferon
and cyclosporine several years earlier.