Inhibitory effect of SNPs on alpha hemolysin, a well-known virulence factor of S.
Alpha hemolysin expression was also effectively inhibited by SNPs treatment.
Conclusion: In general, results revealed formation of spherical silver nanoparticles with inhibitory effects on bacterial growth and antagonist activity on the expression of alpha hemolysin.
Real time PCR (RT-PCR) assay was conducted to assess expression of alpha hemolysin (hla) under SNPs treatment.
As can be seen, a dose-dependent decrease in expression of alpha hemolysin under treatment with various concentrations of SNPs was recorded.
aureus, their influence on expression of alpha hemolysin as a major virulence factor of the pathogen was also evaluated.