The role of
alpha blockers as an adjunctive to ESWL for renal stones has emerged and is generally accepted for the last few years.
Patients in whom
alpha blockers were administered due to the growth of postoperative adenoma and who had been operated on due to urethral stricture, bladder neck contracture or a growing adenoma were also noted and recorded.
know if
alpha blocker drugs, finasteride, or balloon dilation lower the risk of future BPH problems.
The total IPSS score and obstructive and irritative IPSS sub scores were significantly improved after tadalafil therapy in combination with
alpha blocker compared with
alpha blocker alone.
(2) Medical treatment options include Non-Steroidal Anti-Inflamatuar Drugs (NSAIDs),
alpha blockers, steroids and calcium channel blockers.
In the ALLHAT study, diuretic drugs were compared to angiotensin-converting enzyme (ACE) inhibitors that widen blood vessels and decrease resistance, calcium channel blockers that relax vessels by slowing the flow of calcium into the heart and
alpha blockers, which also relax blood vessels.
Nonselective
alpha blockers carry a greater risk of a sudden drop in blood pressure (hypotension) and dizziness upon standing.
(38) The
alpha blockers work by inhibiting [[alpha].sub.1] mediated sympathetic stimulation and thereby promote relaxation of bladder neck and prostatic smooth muscle.
There is evidence that discontinuation of an
alpha blocker after a period of combination therapy may provide durable symptom relief.[sup.6,7] However, these studies lack both long-term data and rates of progression to surgical intervention.
A review of 53 cases of ruptured pheochromocytoma revealed that 17 (32%) of the patients died, and that no mortality occurred among the 12 patients who received an
alpha blocker (for high blood pressure) and fluid infusion therapy before surgery.
Alpha blocker therapy can be withdrawn in the majority of men following initial combination therapy with the dual 5-alpha reductase inhibitor dutasteride.
Now there are three classes of medications:
alpha blockers (Tamsulosin and others), 5-alpha reductase inhibitors (Finasteride and others) and the phosphodiesterase-5 Inhibitor Tadalafil.