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A yellow crystalline principle composed of aloe-emodin and glucose, obtained from aloe; used as a laxative.
Synonym(s): aloetin, barbaloin


A bitter yellow crystalline compound obtained from certain aloes and having laxative properties. Its use in laxatives was banned in the United States in 2002.

aloin (alˑ·ō·in),

n an extract of aloe that consists of several active chemical components, primarily barbaloin, and has cathartic properties. See also barbaloin.


the active constituent in aloes; used at one time as a purgative for horses.
References in periodicals archive ?
1990), leaf skin AP-F1, leaf skin AP-CPase fraction and the 50 kD glycoprotein fraction, commercially available aloin or aloin A (barbaloin), which are the main low molecular weight components of aloe with high contents, were intraperitoneally administered to mice pretreated with Sz at a dose rate of 100 [micro]l/10g body weight (powder dose: approximately 20 mg).
Aloin has a pro-oxidant effect at low concentrations and had an antioxidant effect at higher concentrations.
Last night trading standards officers from Surrey said they had mounted an investigation into the aloin content of all 100 aloe vera juice brands on sale in Britain.
The aloin content of leaf was determined by Hplc (ppm/ 20 mg fresh wt.
Aloin used as a purgative and treatment of chronic constipation and reduction of griping Wallis [27] and Osil et al.
A press release from IASC also cited research from The International Agency for Research on Cancer (IARC), which reviewed aloe vera carcinogenicity information and determined that unpurified whole leaf aloe vera juice is possibly carcinogenic to humans due to its aloin content.
Effect of indomethacin on aloin and 1,8 dioxianthraquinone-induced production of prostaglandins in rat isolated colon.
Ample varieties of phytomolecules such as aloin, ginsenoside, curcumin, epicatcchin, asiaticoside, ziyuglycoside I, magnolol, gallic acid, hydrox-ychavicol, hydroxycinnamic acids, hydroxybenzoic acids, etc.
The prime suspect for causing the tumours is aloin A, which together with other aloe extracts was removed from laxitives sold over the counter in US pharmacies in 2002 because manufacturers had not provided the US Food and Drug Administration (FDA) with sufficient safety information.
However, a lack of federal labeling requirements means consumers cannot be sure whether or how much aloin is present in any given product.
Aloin, used as a bittering agent in beverages and as a pharmaceutical laxative, is extracted.
Analysis of anthraquinones aloe-emodi and aloin by gas chromatography/mass spectrometry.