Approximately 5 years ago, Nicole was also diagnosed with chronic migraines by a local neurologist and has been taking almotriptan of 12.
She reports that she has taken four doses of almotriptan in the past 48 hours with moderate relief.
Nicole is admitted to the ICU as a precaution and immediately discontinued from taking any further fluoxetine, almotriptan, or ondansetron.
However, the recurrence rate within 48 hours after treatment was just 9% in frovatriptan-treated episodes, significantly less than the 24% rate for almotriptan (J.
Major Finding: The menstrual migraine recurrence rate 48 hours after treatment with frovatriptan was 15%, significantly less than the collective 26% rate after treatment with rizatriptan, zolmitriptan, or almotriptan.
To everyone's surprise, the higher dose of almotriptan
did not reach significance for either photophobia or phonophobia," Dr.
Most recently, electriptan and almotriptan
in a series of clinical trials showed a promising pharmacokinetic profile and effective outcome, but a high incidence of adverse
8,440,631, its second patent providing fast acting formulations for triptans, a class of drugs that are effective in treating migraine headaches which include sumatriptan, zolmitriptan, naratriptan, rizatriptan, eletriptan, almotriptan
, naratriptan, rizatriptan, sumatriptan, and zolmitriptan.
registration of their CNS product Almotriptan
for the acute treatment of migraine.
currently is approved in the European Union, and has been marketed in Spain since September 2000.
New products such as Pfizer's eletriptan, Pharmacia & Upjohn's almotriptan
and Vanguard Medica's frovatriptan are expected to help expand the antimigraine market through 2005.