12-14) It is a member of a new class of antifungal agents, the allylamines
, which have a different mechanism of action (squalene epoxidase inhibitor) than the azoles have.
If you have a dry scaly process--with or without the collarettes--you're probably better with an allylamine
, particularly if you use a keratolytic with it, something that has urea or a lactic acid," she said.
7% of the patients who were assigned to the topical allylamine
, compared with 7.
Although the allylamine
terbinafine is not used for treatment of patients with invasive aspergillosis, the drug is highly active against both E.
Posaconazole, a new broad-spectrum triazole, and terbinafine, an allylamine
antifungal, have in vitro activity against these fungi.
Pat Mastin, chief of the NIEHS Cellular, Organ, and Systems Pathobiology Branch, points out that several occupational exposures also have been associated with CVD, including exposures to vinyl chloride (used to produce polyvinyl chloride and industrial solvents), carbon monoxide (a common exhaust gas), and allylamine
(used in ion exchange resins, pharmaceuticals, and water-soluble polymers).
A new formulation of naftifine hydrochloride 2% (Naftin), a potent prescription topical allylamine
antifungal available as a cream or a gel, has shown equivalent efficacy with just 2 weeks of treatment.
1), a synthetic allylamine
antifungal agent, was used as the combination partner, since it is the preferred antifungal drug to treat mycoses produced by dermatophytes (Gokhale and Kulkarni 2000).
Abstract Terbinafine is an oral antimycotic agent that belongs to the allylamine
Terbinafine hydrochloride is a relatively new allylamine
with a broad range of in vitro antifungal activity.
This article is continuation of that work and reports UV surface grafting of WGRT powder with allylamine
Two classes of systemic agents commonly are used for the treatment of onychomycosis: azole antifungal agents--specifically, the triazoles fluconazole and itraconazole--and an agent from the allylamine