is a "super sensitivity of the vulva" which causes normal sensations such as a gentle touch or minimal friction from tight fitting clothes to be exquisitely painful.
Neuropathic pain either at or below the level of injury may be associated with allodynia
(pain caused by a normally nonpainful stimulus) or hyperalgesia (an exaggerated pain response) in the affected dermatomes.
Confirming the effectiveness of the extract and the isolated compound in inflammatory responses, EEMO or AXyl inhibited carrageenan-induced mechanical allodynia
with percentage of inhibition of 40 [+ or -] 6% for EEMO and 82 [+ or -] 8% for AXyl.
A previous study in SCI demonstrated that a DYS classification was associated with burning pain and allodynia
Secondary outcomes included average day and night severity, as well as portions of the Brief Pain Inventory, Clinical Global Impression of Severity Scale, Patient's Global Impression of Improvement, Short-Form McGill Pain Questionnaire, Dynamic Allodynia
, Short Form-36 Health Status Survey, and Euro Quality of Life instrument.
2007, 11: 891-7; Vincler and Eisenach, "Knock down of the alpha 5 nicotinic acetylcholine receptor in spinal nerve-ligated rats alleviates mechanical allodynia
Analysis of the Development of Allodynia
: Correlation Between Migraine Duration and Severity: This retrospective analysis suggests that migraine severity is a significant factor in determining whether a subject will experience central sensitization, as measured by allodynia
This increase in paw-withdrawal threshold in the SCI + minocycline group is consistent with a reduced degree of mechanical allodynia
To assess mechanical allodynia
, rats were placed individually in clear Plexiglas boxes (22 x 14 x 16cm) on elevated wire mesh platforms, to allow access to the ventral surface of the right hindpaw.
PHILADELPHIA -- Patients exhibiting migraine with cutaneous allodynia
respond to triptans only if they take the medication before the allodynia
sets in, said Rami Burstein, Ph.
Other studies documented the absence of significant migration of the injected cells outside the spinal cord, allodynia
induction (increased neuropathic pain due to the injected cells), systemic toxicity or increased mortality in animals receiving GRNOPC1.
Subjects were assessed for adverse events (AEs), including immediate loss of neurologic function or decline in breathing capacity, infection, bladder or bowel function, allodynia
, and neuropathic pain.