The cases of patients suffering from cutaneous allodynia
are rarely seen in NBS.
In pain experiments, mechanical induced allodynia
was suppressed in transgenic mice overexpressing CB2 in the CNS41.
The results showed that FKN-neutralizing antibody significantly lowered CCI-induced thermal hyperalgesia and mechanical allodynia
after treatment, while it had no effect on sham-operated rats (Figure 5).
All patients presented with a disturbance in pinprick sensation, temperature sensation, and/or allodynia
or hyperalgesia, which was in accordance with the clinical manifestations of SFN.
23) A single intrathecal delivery of PDGF B-chain homodimer (PDGF-BB) to naive rats evoked a strong and long-lasting tactile allodynia
in a dose-dependent manner.
predicts outcome of spinal cord stimulation in complex regional pain syndrome type 1.
Treatment protocol for patient with postherpetic neuralgia Year Treatment 2010 2011 TCAs Amitriptyline Amitriptyline Opioids Tramadol Tramadol Antiepileptic Gabapentin Gabapentin drugs Topical TLP TLP analgesics Paracetamol NSAIDs None None VAS 7-8 5-8 Side effects Constipation; Pruritus, psychomotor drift on the fly; restlessness; alopecia; insomnia dry mouth Interventional None None options Allodynia
Pain like Strong burning sensation electrical shock at affected area appeared at noon; at noon and lasted till numbness along 4.
(perception of non-painful stimuli as painful) was reported by 23% of patients.
Chopra, Quercetin attenuates thermal hyperalgesia and cold allodynia
in STZ-induced diabetic rats, Indian J.
, or pain induced by light touch, may also be described.
Post herpetic neuralgia (PHN ) is characterized by ongoing pain and varying degrees of sensory deficits, allodynia
, and hyperalgesia.
Physical examination revealed allodynia
along the right leg and foot, dry skin, and a side-to-side skin temperature discrepancy with the right warmer compared with the left lower limb.