Two out of 21 patients of chronic anemia developed alloantibodies
The frequency of Kell and Rh alloantibodies
was equal in children younger than 12 years (16 of 48; 33.
RH genotyping has revealed that many patients with SCD carry alleles encoding partial D, C, and/or e antigens and that most of these "autoantibodies" are, in fact, alloantibodies
against D, C and e antigens.
Lechler, "Targeting MHC class I monomers to dendritic cells inhibits the indirect pathway of allorecognition and the production of IgG alloantibodies
leading to long-term allograft survival," Journal of Immunology, vol.
The best PRA interpretation is provided by the patient's epidemiological information with regard to risk factors for anti-HLA alloantibodies
formation (multiple pregnancy, poly-transfusion and re-transplants) (HYUN et al.
The persistence and evanescence of blood group alloantibodies
The purpose of this study was to determine the frequency of red cell alloantibodies
and auto-antibodies in thalassemia major children receiving regular blood transfusions.
We have neither had patients with rare blood diseases in our hospital, nor have we had patients with multiple alloantibodies
for whom predeposit autologous transfusion is the only option in chemotherapy.
Research studies by Qatar University (QU) students have revealed important findings on various issues and topics, including energy drink consumption, food safety at Souq Waqif, infection rates of hepatitis G virus (HGV)/GB virus C (GBV-C), adolescent obesity, effect of gender and nationality on sedentary behaviour and dietary habits, nutrition and pain episodes in sickle cell anaemia patients and the presence of alloantibodies
among transfusion-dependent thalassaemia patients.
While these antibodies are not clinically significant as a cause for transfusion reactions, their presence may mask underlying clinically significant alloantibodies
that are capable of causing hemolytic transfusion reactions (HTRs).
In contrast to AHA, immunosuppressive therapy has had limited success in eradicating FVIII alloantibodies
in congenital hemophilia patients (16).
Human platelet antigen-specific alloantibodies
implicated in 1162 cases of neonatal alloimmune thrombocytopenia.