Survival differences were compared in recipients without detectable alloantibodies
and those with de novo and pre-existing alloantibodies
and in those recipients with and those without detectable BKV.
Antenatal first trimester screening enables timely detection of alloantibodies
and treatment of HDFN, and an additional benefit of the screening program is the detection of alloantibodies
relevant in case of transfusion to the mother.
Nine patients (7.76%) developed alloantibodies
and 107 (92.24%) did not.
The destructive power of alloantibodies
of the recipients directed against HLA class I and II molecules varies , depending on the level of antibody , immunoglobulin isotype, target antigen, and the type of organ transplanted [117, 118].
In addition, a survey ascertained that female dogs, even after pregnancy, did not develop any alloantibodies
against RBC antigens during gestation, so they can be used safely as blood donors .
In conclusion, screening for HLA and HPA alloantibodies
is an important adjunctive laboratory test in the diagnosis of platelet refractoriness.
 Kalluri, R., Weber, M., Netzer, K.O., Sun, M.J., Neilson, E.G., and Hudson, B.G., COL4A5 gene deletion and production of post-transplant anti-alpha-3(IV) collagen alloantibodies
in Alport syndrome.
Sensitization to human leukocyte antigens (HLA) in transplant immunology is the occurrence of alloantibodies
in the serum of patients who desire to receive organs, directed towards HLA antigens.
Screening and identifying of erythrocyte alloantibodies
in patients with Thalassemia major referred to Ahvaz Shafa hospital.
the identification of platelet alloantibodies
and for platelet-specific autoantibodies detection7.
Preand post-transfusion and follow-up testing did not show evidence of red blood cell alloantibodies
, making the possibility of a delayed hemolytic transfusion reaction unlikely.
It is thought that hemolytic anemia is related with erythrocyte alloantibodies
(anti-A, anti-B and anti-D) found in IVIG preperation (16-18).