No predominance of eosinophils, no granuloma, no allergic mucin
Histologic examination of the diseased tissue identified allergic mucin
with 70% eosinophils and no fungal hyphae.
In addition, eosinophilic mucin (allergic mucin
) may be observed.
Sinus fungus ball is a form of fungal sinusitis defined as noninvasive chronic fungal sinusitis without inspissated allergic mucin
and occurs in immunocompetent hosts.
The allergic manifestation involves immunocompetent patients and it is characterized by allergic mucin
with eosinophils and Charcot-Leyden crystals, as well as increased serum IgE.
Sinusitis is characterized by the presence of allergic mucin
and elevated IgE; treatment includes surgery plus corticosteroids.
* Identification of allergic mucin
on histopathologic evaluation of material from the sinus.
Presently there were no definite histological criterion for differentiation of allergic from inflammatory polyp but tissue eosinophil count with goblet cells, allergic mucin
with edema and Seromucinous glands are suggestive of allergy.
This inspissated allergic mucin
(classically described as "peanut butter" mucus) may take the form of rubbery plugs that can be expelled from the nose.
b and c (from Allergic Mucin
With and Without Fungus: A Comparative Clinicopathologic Analysis--Lara & Gomez) 4.
They were Type I hypersensitivity, nasal polyposis, characteristic CT scan findings, positive fungal stain/ culture and allergic mucin
with fungal elements.
Allergic fungal sinusitis, also known as allergic mucin
and eosinophilic fungal rhinosinusitis, is an allergic response in the sinonasal tract mucosa to aerosolized fungal allergens, amplified and perpetuated by eosinophils.