9,744,108 B2; The University of Tennessee Research Foundation, Knoxville, TN, has patented a method of treating teeth erosion that entails administering a mouthwash comprised of an alkalinizing agent
to the teeth so as to raise saliva pH to 7.
To study the effect of microenvironment pH changes on the survival of BCSCs, we conducted a study that modulated the pHe of human BCSCs using the alkalinizing agent
sodium bicarbonate (NaHC[O.
In our study, no difference was observed between the patients who received only anthracycline and the patients who received anthracycline and alkalinizing agent or the patients who did not receive anthracycline treatment and received only alkalinizing agent in terms of cardiotoxicity.
Total doses of anthracycline and alkalinizing agents given to the patients with a diagnosis of Hodgkin lymphoma were calculated.
On the other hand, cardiotoxicity cases are reported in patients who use usual doses of alkalinizing agents, although cardiomyopathy is known to develop especially in patients with bone marrow transplant following treatment with high doses of alkalinizing agents (14).
Specifically, agents that increase gastric pH (eg, proton pump inhibitors) as well as urinary alkalinizing agents
(eg, acetazolamide, some thiazide diuretics) increase serum amphetamine concentrations.
Its use eliminates the employment of alkalinizing agents
(such as lime or soda), does not add metals to the process and reduces the volume of sludge to be disposed.
Common side effects of alkalinizing agents
include nausea, abdominal bloating and diarrhea.
Thus, ingestion of alkalinizing agents mentioned above by increasing the extracellular pH may create a favourable pH gradient for efflux of intracellular lactate and [H.
Numerous studies have assessed the effect of preexercise administration of alkalinizing agents on performance in different types of exercise (Burke et al.