alkaline phosphatases

alkaline phosphatases

ENZYMES with an optimum pH in the alkaline range, that break down phosphate bonds in compounds. They are widely distributed in the body, and are released into the blood in large quantites in a number of conditions including obstructive JAUNDICE and certain bone diseases. This forms the basis of a common biochemical test.
References in periodicals archive ?
Alkaline phosphatases have been nearly a lifelong labor for George Bowers and Robert McComb.
The point in assessing the bone-specific fraction of alkaline phosphatases is to determine whether or not this advances diagnostic sensitivity.
Total and bone-specific alkaline phosphatases in haemodialysis patients with chronic liver disease.
Heat inactivation in the study of human alkaline phosphatases. Ann Intern Med.
Millan, Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology, John Wiley & Sons, 2006.
Alkaline phosphatases (APs) have been continuously and extensively investigated for over 50 years.
Total bone and liver alkaline phosphatases in plasma: biological variations and reference limits.
Human alkaline phosphatases. Evidence of three isoenzymes (placental, intestinal and liver-bone-kidney-type) by lectin-binding affinity and immunological specificity.
Differences between the sugar moieties of liver and bone-type alkaline phosphatases: a re-evaluation.
The bone isoform of alkaline phosphatase (ALP) is a member of the so-called tissue-nonspecific isoenzyme family, which also comprises the liver and kidney isoforms.