alkaline phosphatases

alkaline phosphatases

ENZYMES with an optimum pH in the alkaline range, that break down phosphate bonds in compounds. They are widely distributed in the body, and are released into the blood in large quantites in a number of conditions including obstructive JAUNDICE and certain bone diseases. This forms the basis of a common biochemical test.
References in periodicals archive ?
Heat inactivation in the study of human alkaline phosphatases.
Alkaline phosphatase (ALP) isoenzymes mainly exist in bones, liver, intestine, placenta, mammary glands, kidneys, and leukocytes.
Alkaline phosphatases (APs) have been continuously and extensively investigated for over 50 years.
Alkaline Phosphatases are a group of enzymes found primarily the liver (isoenzyme ALP-1) and bone (isoenzyme ALP-2).
Total bone and liver alkaline phosphatases in plasma: biological variations and reference limits.
Improved electrophoretic resolution of bone and liver alkaline phosphatases resulting from partial digestion with neuraminidase.
Alkaline phosphatases have been nearly a lifelong labor for George Bowers and Robert McComb.
The point in assessing the bone-specific fraction of alkaline phosphatases is to determine whether or not this advances diagnostic sensitivity.
Osteoblasts are rich in alkaline phosphatase; however, alkaline phosphatase, an enzyme associated with the plasma membrane of cells, is also found in liver, intestine, and placenta (15), all of which may contribute to the total amount of alkaline phosphatase found in blood.
The bone isoform of alkaline phosphatase (ALP) is a member of the so-called tissue-nonspecific isoenzyme family, which also comprises the liver and kidney isoforms.