alkaline phosphatase isoenzyme

Any of the organ-specific alkaline phosphatase isoenzymes: liver, bone, intestine and placenta. Intestinal AP occurs almost exclusively in individuals with blood group B or O and is increased 8 hours after a fatty meal; placental AP first appears in the 2nd trimester of pregnancy, accounts for half of all AP in the 3rd trimester and drops to normal levels 1 month postpartum; the Regan isoenzyme resembles the placental AP and is present in some patients with cancer. APIs should not be measured if the total AP levels are within the lab’s reference range, as the results have little significance; these tests are only semi-quantitative and are variable.

alkaline phosphatase isoenzyme

Clinical chemistry Any of the organ-specific alkaline phosphatase isoenzymes: liver, bone, intestine and placenta; intestinal AP occurs almost exclusively in individuals with blood group B or O and is ↑ 8 hrs after a fatty meal; placental AP first appears in the 2^nd trimester of pregnancy, accounts for half of all AP in the 3^rd trimester and drops to normal levels 1 month post partum; the Regan isoenzyme resembles the placental AP and is present in some Pts with cancer. See Alkaline phosphatase.

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alkaline phosphatase

References in periodicals archive ?

Quantification of liver alkaline phosphatase isoenzyme activity using heat inactivation and phenylalanine inhibition techniques: Comparison of two methods.

Effect of incubation period on measurement of alkaline phosphatase enzyme activity at 37[degrees]C

University Hospital Southampton NHS Foundation Trust invite tenders from suitably qualified suppliers for the provision of electrophoretic analysis of serum and urine proteins, serum and urine immunofixation, alkaline phosphatase isoenzyme electrophoresis, alpha-1-antitrypsin phenotyping, which must include Capillary Zone Electrophoresis for the analysis of serum proteins and serum immunotyping.

Reagents for electrophoresis

Interpretation and clinical significance of alkaline phosphatase isoenzyme patterns.

Increased serum alkaline phosphatase activity originating from neutrophilic leukocytes

Further studies are needed to know the alkaline phosphatase isoenzyme patterns in malignant diseases.

Correlation of serum lipid profile, serum calcium, alkaline phosphatase and serum protein with histopathological grading and staging in head and neck cancer

Relation between Alkaline Phosphatase Isoenzymes and Disease Activity in Rheumatoid Arthritis.

Study of serum adenosine deaminase and alkaline phosphatase in rheumatoid arthritis

Alkaline phosphatase isoenzymes in serum and bronchoalveolar lavage from patients with bronchopulmonary disease.

Alkaline phosphatase activity in bronchoalveolar lavage of police horses in Rio de Janeiro State, Brazil/Atividade da fosfatase alcalina no lavado broncoalveolar de equinos de policiamento montado no Estado do Rio de Janeiro

Effect of Chromium and cadmium on the activity of alkaline phosphatase isoenzymes with molecular weights of heavy and light in rats.

Investigating the effect of imipramine medication on enzymes changes of AST, ALT and ALK in adult female rats

Analysis of alkaline phosphatase isoenzymes also did not reveal anyone with predominant bone isoenzyme.

Are elderly Asians in Britain at a high risk of vitamin D deficiency and osteomalacia?

The following biochemical indexes were analyzed on freshly collected serum from patients: alpha-fetoprotein (AFP), carcinoembryonic antigen, lactate dehydrogenase (LD), LD isoenzymes, alkaline phosphatase and alkaline phosphatase isoenzymes, [gamma]-glutamyltransferase (GGT) and the GGTL isoenzyme (i.

Serum [gamma]-glutamyltransferase isoform complexed to LDL in the diagnosis of small hepatocellular carcinoma

Two new methods for separating and quantifying bone and liver alkaline phosphatase isoenzymes in plasma.

Analytical and clinical performance characteristics of tandem-MP ostase, a new immunoassay for serum bone alkaline phosphatase

Clinical evaluation of high-performance affinity chromatography for the separation of bone and liver alkaline phosphatase isoenzymes.

Direct comparison of performance characteristics of two immunoassays for bone isoform of alkaline phosphatase in serum

Age and sex distribution of alkaline phosphatase isoenzymes by agarose electrophoresis.

Relations between intestinal alkaline phosphatase activity and insulin secretion in obese patients