aldosteronism


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Related to aldosteronism: secondary aldosteronism

aldosteronism

 [al-dos´ter-ōn-izm″, al″do-ster´ōn-izm]
an abnormality of electrolyte metabolism produced by excessive secretion of aldosterone, it may be primary or occur secondarily in response to extra-adrenal disease. There may be hypertension, hypokalemia, alkalosis, muscular weakness, polyuria, and polydipsia. Called also hyperaldosteronism.
primary aldosteronism that arising from oversecretion of aldosterone, characterized typically by hypokalemia, alkalosis, muscular weakness, polyuria, polydipsia, hypertension, cardiac irregularity, and tetany. The most common etiologic factors are adrenal adenoma, idiopathic hyperplasia of the adrenal cortex, and occasionally carcinoma of the adrenal gland. Most adenomas affect only one of the two glands and therefore can be removed surgically without depriving the patient of a sufficient supply of adrenal cortical hormones. If removal of both glands is necessary, this creates a serious and potentially fatal insufficiency of the hormones. Called also Conn's syndrome.
pseudoprimary aldosteronism that caused by bilateral adrenal hyperplasia and having the same signs and symptoms as primary aldosteronism.
secondary aldosteronism that due to extra-adrenal stimulation of aldosterone secretion; it is commonly associated with edematous states, as in nephrotic syndrome, hepatic cirrhosis, heart failure, and accelerated hypertension.

al·dos·ter·on·ism

(al-dos'tĕr-on-izm),
A disorder caused by excessive secretion of aldosterone.
Synonym(s): hyperaldosteronism

aldosteronism

(ăl-dŏs′tə-rō-nĭz′əm, ăl′dō-stĕr′ə-)
n.
A disorder marked by excessive secretion of aldosterone, characterized by weakness, cardiac irregularities, and abnormally high blood pressure.

al·dos·ter·on·ism

(al-dos'tĕr-ŏn-izm)
A disorder caused by excessive secretion of aldosterone.
Synonym(s): hyperaldosteronism.

aldosteronism

The condition caused by excessive secretion of the adrenal HORMONE aldosterone. It features muscle weakness, high blood pressure (HYPERTENSION), ALKALOSIS, excessive urinary output and thirst.

Aldosteronism

A disorder caused by excessive production of the hormone aldosterone, which is produced by a part of the adrenal glands called the adrenal cortex. Causes include a tumor of the adrenal gland (Conn's syndrome), or a disorder reducing the blood flow through the kidney. This leads to overproduction of renin and angiotensin, and in turn causes excessive aldosterone production. Symptoms include hypertension, impaired kidney function, thirst and muscle weakness.

al·dos·ter·on·ism

(al-dos'tĕr-ŏn-izm)
A dis-order caused by excessive secretion of aldosterone.
References in periodicals archive ?
New insights into aldosterone-producing adenomas and hereditary aldosteronism: mutations in the K+ channel KCNJ5.
Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism. Hypertension 2002;40:897-902.
Role of radiology in the management of primary aldosteronism. Radiographics 2007; 27: 1145-1157.
More recently LC-MS/MS has come to the forefront for not only routine measurements of serum, urinary free, or salivary cortisol (8-10) but also multisteroid profiling in disorders of adrenocortical function such as congenital adrenal hyperplasia (11, 12), adrenal insufficiency (12, 13), and primary aldosteronism (14, 15).
Fineberg, "The diagnosis of primary aldosteronism and separation of two major subtypes," Archives of Internal Medicine, vol.
Primary aldosteronism (PA) as an endocrine hypertension syndrome was first described by Conn in 1955 [1].
Surgical treatment of primary aldosteronism is the definitive therapy of HP induced by Conn's syndrome; therefore, the serious events that hypertension and paralysis trigger will be prevented (7).
Primary, idiopathic, or essential hypertension is defined as high blood pressure, in which secondary causes such as renal failure, renovascular disease, pheochromocytoma, aldosteronism, or other causes of secondary hypertension or Mendelian forms (monogenic) are not present.
Primary aldosteronism is a disease caused by increased aldosterone secreted in the zona glomerulosa of the adrenal cortex, with the symptoms of hypertension and hypokalemia as its main clinical manifestations.
Adrenal causes of hypertension: pheochromocytoma and primary aldosteronism. Rev Endocr Metab Disord 2007;8:309-20.