ALDOB(redirected from aldolase B, fructose-bisphosphatase)
ALDOBA gene on chromosome 9q21.3-q22.2 that encodes aldolase B (fructose-bisphosphate aldolase), a glycolytic enzyme that catalyses the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. It is expressed in the developing embryo and in adult muscle, adult liver, kidney and intestine.
ALDOB mutations cause hereditary fructose intolerance.
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