aldolase


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al·dol·ase

(al'dō-lās),
1. Generic term for aldehyde-lyase.
2. Name sometimes applied to fructose-1,6-bisphosphate aldolase.

aldolase

/al·do·lase/ (al´do-lās)
2. an enzyme that acts as a catalyst in the production of dihydroxyacetone phosphate and glyceraldehyde phosphate from fructose 1,6-bisphosphate. It occurs in several isozymes, one of which is deficient in hereditary fructose intolerance.

aldolase

(ăl′də-lās′)
n.
Any of a class of enzymes that reversibly catalyze the cleavage of carbon-carbon bonds, especially the cleavage of sugars into three-carbon fragments during glycolysis.

aldolase

[al′dəlās]
enzyme found in muscle tissue that catalyzes the step in anaerobic glycolysis involving the breakdown of fructose 1,6-biphosphate to glyceraldehyde 3-phosphate. The enzyme can also catalyze the reverse reaction. Normal adult findings are 3 to 8.2 Sibley-Lehninger units/dL or 22 to 59 mU at 37° C. See also glycolysis.

aldolase

Clinical chemistry A serum enzyme that cleaves fructose 1,6-diphosphate to dihydroxyacetone phosphate and glyceraldehyde-3-phosphate in the muscles to produce energy; aldolase is distributed in all tissues and ↑ in skeletal muscle disease or injury, metastatic CA, CML, megaloblastic anemia, hemolytic anemia, or infarction; it is measured in suspected myopathies, as the intensity of ↑ reflects the severity of disease; aldolase may also be ↑ early in Pts who later develop muscular dystrophy and can also be used to monitor steroid therapy in inflammatory myopathies Ref range 3.1-7.5 U/L; aldolase is ↑ in Duchenne's muscular dystrophy, dermatomyositis, polymyositis, trichinosis

Aldolase

An enzyme, found primarily in the muscle, that helps convert sugar into energy.
Mentioned in: Aldolase Test

aldolase

an enzyme involved in the Embden-Meyerhof or glycolytic pathway which reversibly catalyzes the reaction fructose-1,6-bisphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. Present in all cells and may be measured in the serum as an indicator of muscle, heart or liver disease. Called also ALS and ALD.
References in periodicals archive ?
Spot Accession number number Protein name M17 K22E Keratin, type II cytoskeletal 2 epidermal M18 Q6NTA2 HNRNPL protein M19 Q32Q12 Nucleoside diphosphate kinase M20 ALDOA Fructose-bisphosphate aldolase A M21 PEBP1 Phosphatidylethanolamine-binding protein 1 M22 PGAM1 Phosphoglycerate mutase 1 N13 GMFB Glia maturation factor beta N14 HSPB1 Heat shock protein beta-1 N15 TP1S Triosephosphate isomerase M23 PGAM1 Phosphoglycerate mutase 1 M24 ENOA Alpha-enolase Spot Theoretical Theoretical Number of number Gene name Mr pl peptide Score M17 KRT2 65,678.
Also zinc is part of some enzymes structure, such as: Alkaline Phosphatase, phosphatides lipase, Carboxypeptidase, RNA polymerase, Dehydrogenase and Aldolase (Pandy et al, 2002).
1997) and it is the precursor of glycine and serine through the activities of the Thr enzyme aldolase and desidrogenase (CORZO et al.
105, P40433), fructosebiphosphate aldolase (ALD1, EC 4.
Fructose-1,6- It is a heat-stabile and bi-functional protein bisphosphate that represents the pace-making ancestral aldolase gluconeogenic enzyme.
Some MRDTs detect the presence of aldolase, which is not species specific but rather is found in all malaria species.
Selenomethionine can be deposited in tissues and be taken up also by myoglobin, cytochrome C, myosin, aldolase and nucleo-proteins.
Workup for suspected FSHD includes laboratory tests for muscle enzymes like creatinine kinase and aldolase.
cytoskeletal 2A 1098 42059 ACTC_STRPU OS = Strongylocentrouce purpuratus tr|Q70JA0| Nectin OS = 701 108817 Q70JA0_PARLI Paracentrous lividus tr|O44344| Complemenl component 563 187929 O44344_STRFU C3 OS = Strongylocentrouce purpuratus tr|Q86RA9| Amassin OS = 287 57012 Q86RA9_STRPU Strongylocentrouce purpuratus tr|A9LYL6| Putative uterine-ovary 180 45789 A9LYL6_HELTB speeilie-44 protein OS = Heliocidaris tuberculata tr|Q6PTFl| Fructose- bisphosphatc 171 21958 Q6PTF1_STRPU aldolase (Fragment) OS = Strongylocentrouce purpuratus tr|D5H3J3| Ubiquitin OS = 154 14927 D5H3J3_P5AMI Psammechinus miliaris sp|P02290| Histone H2B.
A diferenciacao celular foi avaliada pela dosagem de triglicerides no caso da diferenciacao adipogenica, e da dosagem de creatinofosoquinase, desidrogenase latica e aldolase para diferenciacao miogenica, ambos com o metodo enzimatico colorimetrico utilizando o aparelho ADVIA 2400 (Bayer[R]).
The antimicrobial activity of acidic EO water can be categorized by six mechanisms: inhibition of glucose oxidation (mainly the aldolase enzyme), disruption of protein synthesis, reactions with nucleic acids, unbalance of metabolism after destruction of key enzymes, induction of DNA lesions, and inhibition of oxygen uptake and oxidative phosphorylation.