alcoholic cardiomyopathy


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cardiomyopathy

 [kahr″de-o-mi-op´ah-the]
a general diagnostic term designating primary myocardial disease.
alcoholic cardiomyopathy a congestive cardiomyopathy resulting in cardiac enlargement and low cardiac output occurring in chronic alcoholics; the heart disease in beriberi (thiamine deficiency) is also associated with alcoholism.
congestive cardiomyopathy a syndrome characterized by cardiac enlargement, especially of the left ventricle, myocardial dysfunction, and congestive heart failure.
hypertrophic cardiomyopathy an increase in heart muscle weight, particularly of the left ventricle and often involving the interventricular septum; it may affect the flow of blood from an atrium into the ventricle or out from the ventricle. This type of cardiomyopathy is frequently associated with idiopathic hypertrophic subaortic stenosis. Called also asymmetrical septal hypertrophy.
hypertrophic obstructive cardiomyopathy a form of hypertrophic cardiomyopathy in which the location of the septal hypertrophy causes obstructive interference to left ventricular outflow. See also asymmetrical septal hypertrophy.
infiltrative cardiomyopathy myocardial disease resulting from deposition in the heart tissue of abnormal substances, as may occur in amyloidosis, hemochromatosis, and other disorders.
primary cardiomyopathy that in which the basic pathologic process involves the myocardium itself and not other cardiac structures; the condition is of unknown etiology and not part of a disease affecting other organs.
restrictive cardiomyopathy a form in which the ventricular walls are excessively rigid, impeding ventricular filling; it is marked by abnormal diastolic function but normal or nearly normal systolic function.
secondary cardiomyopathy any form that is due to another cardiovascular disorder or is a manifestation of a systemic disease such as sarcoidosis.

al·co·hol·ic car·di·o·my·op·a·thy

myocardial disease occurring in some patients with long-term alcoholism; may result from alcohol toxicity, or thiamin deficiency, or be of unknown pathogenesis.

alcoholic cardiomyopathy

A condition linked to chronic alcohol excess. It is a major cause of dilated cardiomyopathy, and is characterised by severe left ventricular dysfunction, which may present as ventricular fibrillation or sudden death.
Clinical findings Heart failure, anasarca and peripheral oedema, anorexia, shortness breath, dependent dyspnoea, oliguria, nocturia, palpitations, thready pulse.
Diagnosis Heart murmurs, EKG changes, enlarged heart by imaging.
Management Alcohol abstinence (if possible), reduced sodium, fluid restriction, ACE inhibitors, beta blockers, diuretics; pacemaker, heart transplant.
Mortality Up to 80% die within 3 years.

alcoholic cardiomyopathy

 A clinicopathologic state induced by chronic alcoholism, and a major cause of dilated cardiomyopathy, characterized by severe left ventricular dysfunction, associated with a 40-80% 3-yr mortality, and it may present as sudden death or ventricular fibrillation

al·co·hol·ic car·di·o·my·op·athy

(ACM) (al-kō-holik kahrdē-ō-mī-opă-thē)
Heart disease occurring in some patients with long-term alcoholism.

al·co·hol·ic car·di·o·my·op·athy

(al-kō-holik kahrdē-ō-mī-opă-thē)
Myocardial disease in some patients with long-term alcoholism; may result from alcohol toxicity, or thiamin deficiency, or unknown pathogenesis.
References in periodicals archive ?
Comparison of alcoholic cardiomyopathy in women versus men.
Evidence of apoptosis in alcoholic cardiomyopathy. Human Pathology 37(8):1100-1110, 2006.
Although the natural course of chronic alcoholic cardiomyopathy could not be defined clearly, it has been shown that abstaining from alcohol is associated with improvement in ejection fraction [20, 21].
Our present study showed the limitations of conventional echocardiographic evaluation of early deterioration in cardiac systolic function and the value of speckle tracking echocardiography in subclinic alcoholic cardiomyopathy. The novel echocardiographic modalities would allow for demonstration of heavy alcohol consumption outcomes on systolic function.
Experimental assessment of the role of acetaldehyde in alcoholic cardiomyopathy. Biol Proced Online.
Since, in the present study, the sole cause of dilatation in heart chambers was alcohol, it can be labelled as alcoholic cardiomyopathy. Catherine et all gave 20% ethanol in drinking water to adult chickens of two months' age.14 They specifically studied left ventricle through echocardiography and histopathology.
Alcoholic cardiomyopathy accounts for 33% of all dilated cardiomyopathies.
Long-term heavy drinking can cause the heart to become enlarged and lose some of its ability to contract, a condition known as alcoholic cardiomyopathy. These symptoms include shortness of breath and an insufficient blood flow to the rest of the body.
Hospitalizations Alcohol-attributable condition Male Female Total Lip & Oropharyngeal Cancer 756 164 919 Oesophageal Cancer 696 146 842 Liver Cancer 316 94 410 Laryngeal Cancer 722 108 830 Breast Cancer 0 898 898 Alcoholic Psychoses 4,144 1,225 5,369 Alcohol Dependence Syndrome 10,670 3,646 14,316 Alcohol Abuse 1,966 1,163 3,129 Epilepsy 655 569 1,224 Alcoholic Polyneuropathy 41 131 54 Hypertension 329 1341 462 Alcoholic Cardiomyopathy 205 17 222 Cardiac Dysrhythmias 2,984 1,620 4,604 Heart Failure & III-defined 359 211 570 Stroke 900 74 973 Oesophageal Varices 254 96 350 Gastro-oesophag.
KEY WORDS: animal model; chronic AODE (effects of AOD [alcohol or other drug] use, abuse, and dependence); in vitro study; body part; body fluid; alcoholic liver disorder; alcoholic cardiomyopathy; fetal alcohol syndrome; alcohol-related neurodevelopment disorder; ethanol metabolism
The, article then summarizes the results of studies aimed at identifying the mechanisms underlying alcohol-induced liver damage, alcoholic cardiomyopathy, and FAS.
1997) suggest that alcoholic cardiomyopathy can improve with abstinence, which is therefore a cornerstone of therapy.