ADH4

(redirected from alcohol dehydrogenase 4)

ADH4

A gene on chromosome 4q21-24 that encodes a class-II alcohol dehydrogenase 4-pi subunit of the alcohol dehydrogenase family, which metabolise various substrates, including ethanol, retinol, other aliphatic
alcohols, hydroxysteroids and lipid peroxidation products. Class-II alcohol dehydrogenase exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols.

References in periodicals archive ?

Today, humans rely on an enzyme called alcohol dehydrogenase 4, or ADH4, to break down ethanol.

Taste for alcohol 'originated 10mn yrs ago in common ancestor of humans and chimps'

Identification of a FOXA-dependent enhancer of human alcohol dehydrogenase 4 (ADH4).

Genes encoding enzymes involved in ethanol metabolism

Polymorphism of the human alcohol dehydrogenase 4 (ADH4) promoter affects gene expression.

The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants