alcohol dehydrogenase


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Related to alcohol dehydrogenase: Aldehyde dehydrogenase

al·co·hol de·hy·dro·gen·ase (ADH),

(al'kŏ-hol dē-hi-droj'e-nās),
An oxidoreductase that reversibly converts an alcohol to an aldehyde (or ketone) with NAD+ as the hydride acceptor; for example, ethanol + NAD+ ⇄ acetaldehyde + NADH.
See also: alcohol dehydrogenase (acceptor), alcohol dehydrogenase (NADP+).

alcohol dehydrogenase

n.
Any of a class of enzymes that catalyze the oxidation of alcohols to aldehydes or ketones.

al·co·hol de·hy·dro·gen·ase

(ADH) (al'kŏ-hol dē-hī-droj'en-ās)
An oxidoreductase that reversibly converts an alcohol to an aldehyde (or ketone) with NAD+ as the H acceptor. For example, ethanol + NAD+↔ acetaldehyde+ NADH. Plays an important role in alcoholism.
References in periodicals archive ?
Alcohol dehydrogenase polymorphism of Drosophila melanogaster: Aspects of alcohol and temperature variation in the larval environment.
Taherzadeh, "Inhibition effects of furfural on alcohol dehydrogenase, aldehyde dehydrogenase and pyruvate dehydrogenase," Biochemical Journal, vol.
Ohno, "Dose and time changes in liver alcohol dehydrogenase (ADH) activity during acute alcohol intoxication involve not only class I but also class III ADH and govern elimination rate of blood ethanol," Legal Medicine, vol.
The management of methanol and ethylene glycol poisoning includes supportive care, respiratory support if needed (mechanical ventilation), the use of cofactors to stimulate formation of less toxic metabolites (see Figures 1 and 2), and the use of either an alcohol dehydrogenase inhibitor (fomepizole) or ethanol, which work by displacing the toxic alcohol and preventing it from being metabolized by alcohol dehydrogenase.
For the estimation of the allelic and genotypic frequencies of the genes of enzymes alcohol dehydrogenase, aldehyde dehydrogenase and the cytochrome p450 2E1 were used the program of genetic data analyses GENEPOP[R] version 3.413.
Determination of the effects of alcohol dehydrogenase (ADH) 1B and ADH1C polymorphisms on alcohol dependence in Turkey.
Subsequently, we proposed the hypothesis of an enzymatic oxidation mechanism involving alcohol dehydrogenase (ADH) and clarified the existence of both original ADH existing in wood right after harvest and induced ADH on the surface of processed wood in response to reaction with the ethanol added as a solvent in adhesives or paints (Tohmura et al.
Biochemistry and Pathophysiology of Alcohol Metabolism After administration, alcohol (ethanol) is metabolized to acetaldehyde by the enzymatic action of alcohol dehydrogenase with NAD+ as a coenzyme.
Many of the chronic effects of alcohol is through it's metabolism by alcohol dehydrogenase and microsomal pathways of ethanol oxidizing system.
The first, and rate-limiting, step in this metabolic pathway is catalyzed by alcohol dehydrogenase, the same enzyme responsible for ethanol metabolism (3).
Ma, "Characterization of a zinc-containing alcohol dehydrogenase with stereoselectivity from the hyperthermophilic archaeon Thermococcus guaymasensis," Journal of Bacteriology, vol.
They also have a lower activity of a metabolizing enzyme in the stomach called alcohol dehydrogenase (ADH).

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