alanine-glyoxylate aminotransferase

al·a·nine-gly·ox·y·late a·mi·no·trans·fer·ase

(al'-a-nē-glī-oks'i-lāt a-mē'nō-tranz'fĕr-ās),
An enzyme that reversibly catalyzes the transfer of an amino group of l-alanine to glyoxylate, thus producing pyruvate and glycine. An inherited disorder that results in an alteration of alanine-glyoxylate aminotransferase activity is associated with primary hyperoxaluria type I.
References in periodicals archive ?
Cutaneous oxalosis can occur as a primary disorder, when patients have metabolic errors and lack alanine-glyoxylate aminotransferase or D-glycerate dehydrogenase.
13) However, a genetic polymorphism present in up to 20% of Caucasian groups called P11L codes for a protein with 3 times less activity of alanine-glyoxylate aminotransferase (AGT) than the predominant normal activity polymorphism, leading to excessive endogenous production of oxalates.
The organ distribution of human alanine-2-oxoglutarate aminotransferase and alanine-glyoxylate aminotransferase.