Aspartate transferase and alanine transferase
were determined by the methods of Reitman and Frankel (1957).
, aspartate trasnferrase, alkaline phosphatase and gamma-glutamyl transpeptidase levels were 946, 1047, 396 and 203 U/L, respectively.
An 80-year old lady was referred to a gastroenterology clinic in August 2009 with deranged liver function tests; alkaline phosphatase 180 IU/L (35-120), alanine transferase
147 IU/L (<40), gamma glutamyl transferase 384 IU/L (<45) and globulins 45 g/L (20-35).
Patients in the teriflunomide group experienced more nausea, diarrhea, increases in alanine transferase
, and hair thinning than did those in the placebo group, but these effects were mild.
98 mg/ dL), and abnormal liver function (aspartate aminotransferase 49 U/L and alanine transferase
At the end of therapy, normalization of alanine transferase
occurred in 14/33 treated patients (42.
The most common grade 3-4 biochemical abnormalities were alanine transferase
elevation (13%), bilirubin (25%), hypophosphatemia (32%), lipase elevation (44%), and hyperglycemia (33%), Dr.
As a result, in mice administered the anti-CXCL10 neutralizing antibody the serum alanine transferase
(ALT3) level was significantly lower, and histologically too the area of necrotized hepatic cells was strikingly reduced.
Sixty-nine percent (38/55) of patients who received Hepsera for 240 weeks exhibited improvement in liver function, as measured by normalization of serum alanine transferase
6 Alkaline phosphatase (IU/L) 240 83 125-476 Aspartate transferase (IU/L) 46 26 20-128 Alanine transferase
(IU/L) (c) 81 51 10-210 Sodium (mg/dL) 146 4 141-152 Chloride (mg/dL) 104 4 97-111 Platelets (x[10.
Serum alanine transferase
levels declined in patients receiving rosglitazone, perhaps because the drug decreased liver fat content.