alanine transaminase


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Related to alanine transaminase: Aspartate transaminase

alanine transaminase

 [al´ah-nēn trans-am´ĭ-nās]
an enzyme that catalyzes the reversible transfer of an amino group from alanine to α-ketoglutarate to form pyruvate and glutamate. Normally present in many tissues and body fluids, especially in the liver, it is released into the serum as a result of tissue injury; the serum concentration is increased particularly when there is acute damage to hepatic cells, as in viral or toxic hepatitis, infectious mononucleosis, and obstructive jaundice. Called also alanine aminotransferase and glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase (ALT),

(al'ă-nēn a-mē'nō-tranz'fer-ās),
An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); one d-alanine transaminase effects the same reaction, but using d-alanine and d-glutamate. Serum concentration is increased in viral hepatitis and myocardial infarction.

alanine transaminase

/al·a·nine trans·am·i·nase/ (trans-am´ĭ-nās) an enzyme normally present in serum and body tissues, especially in the liver; it is released into the serum as a result of tissue injury, hence the concentration in the serum may be increased in patients with acute damage to hepatic cells.

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās)
An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās)
An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase,
alanine transaminase.
References in periodicals archive ?
Alanine transaminase level in U/L; meanSD (range)###108151 (6 - 2521)###5563 (6 - 609)###less than 0.
Then blood sample from the same birds were drawn from wing vein (vena cutanea ulnaris) on days 33, 37 and 41 after medication for determination of serum values of following parameters; Aspartate Transaminase (Thomas, 1998), Alanine Transaminase, Uric acid, Alkaline phosphatase (ALP) (Bessey et al.
Methyl paraben (CAS No: 99-76-3) (Fluka Chemika, Germany), HPLC grade acetone (Merck), anti-carp vitellogenin ELISA (Cayman chemicals, MI, USA), enzymes kits for alanine transaminase, aspartate transaminase, alkaline and acid phosphatase (Siddham Chemicals, Nagpur) and clove oil containing average Eugenol concentration of 8%) (Nav Niketan Pharmaceuticals, Mumbai, India) were purchased.
In our study the laboratory parameter was observed alanine transaminase to be lower in dengue patients than the reference ranges.
2 mmol/L Creatinine 91 [micro]mol/L Albumin 47 g/L Bilirubin 8 [micro]mol/L Alkaline phosphatase 93 IU/L Alanine transaminase 14 IU/L Corrected calcium 2.
Levels of the liver enzymes aspartate aminotransferase (AST) and alanine transaminase (ALT) did not differ between the naltrexone and placebo group at baseline or at 1 month of treatment, nor did the percentage of individuals with levels out of the normal range: 3.
LIVER FUNCTION TEST RESULTS Parameter (normal range) Dec 07 Jan 08 Feb 08 June 08 TBil (0-17) 3 6 87 17 ALT (0-40) 111 80 122 40 AST (0-40) 126 60 268 48 ALP (40-120) 277 190 332 100 GGT (0-35) 295 196 507 96 TBil = total bilirubin ([micro]mol/l); ALT = alanine transaminase (IU/l); AST = aspartate transaminase (IU/l); ALP = alkaline phosphatase (IU/l); GGT = gamma-glutamyltranspeptidase (IU/l).
Serum alkaline phosphatase (ALP), aspartate transaminase (APT) and alanine transaminase (ALT) activities of rabbits administered sertraline, clozapine, amitriptyline, imipramine or saline for 28 days are presented in Table 7.
Lamivudine is an oral nucleoside analog that inhibits HBV replication and markedly normalizes alanine transaminase levels.
9]/l; mean cell volume 82 fl; peripheral smear showed anisocytosis, target cells and schistocytes; lactate dehydrogenase 612 U/l; alanine transaminase 446 U/l; aspartate transaminase 191 U/l; total bilirubin 34 mmol/l; direct bilirubin 12 mmol/l; total protein 46 g/l; albumin 20 g/dl; international normalised ratio 2.
The only statistical difference was seen in a slightly higher average in the alanine transaminase (ALT) levels (mean 46 [+ or -] 21.
Aspartate transaminase (AST), alanine transaminase (ALT), TNF-[alpha] (ELISA) and IL-6 levels (ELISA) were also determined in serum samples.