alanine transaminase


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Related to alanine transaminase: Aspartate transaminase

alanine transaminase

 [al´ah-nēn trans-am´ĭ-nās]
an enzyme that catalyzes the reversible transfer of an amino group from alanine to α-ketoglutarate to form pyruvate and glutamate. Normally present in many tissues and body fluids, especially in the liver, it is released into the serum as a result of tissue injury; the serum concentration is increased particularly when there is acute damage to hepatic cells, as in viral or toxic hepatitis, infectious mononucleosis, and obstructive jaundice. Called also alanine aminotransferase and glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase (ALT),

(al'ă-nēn a-mē'nō-tranz'fer-ās),
An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); one d-alanine transaminase effects the same reaction, but using d-alanine and d-glutamate. Serum concentration is increased in viral hepatitis and myocardial infarction.

alanine transaminase

/al·a·nine trans·am·i·nase/ (trans-am´ĭ-nās) an enzyme normally present in serum and body tissues, especially in the liver; it is released into the serum as a result of tissue injury, hence the concentration in the serum may be increased in patients with acute damage to hepatic cells.

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās)
An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās)
An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase,
alanine transaminase.
References in periodicals archive ?
Table 7: Serum alkaline phosphatase (ALP), aspartate transaminase (APT) and alanine transaminase (ALT) activities of rabbits administered (i.
LIVER FUNCTION TEST RESULTS Parameter (normal range) Dec 07 Jan 08 Feb 08 June 08 TBil (0-17) 3 6 87 17 ALT (0-40) 111 80 122 40 AST (0-40) 126 60 268 48 ALP (40-120) 277 190 332 100 GGT (0-35) 295 196 507 96 TBil = total bilirubin ([micro]mol/l); ALT = alanine transaminase (IU/l); AST = aspartate transaminase (IU/l); ALP = alkaline phosphatase (IU/l); GGT = gamma-glutamyltranspeptidase (IU/l).
The only statistical difference was seen in a slightly higher average in the alanine transaminase (ALT) levels (mean 46 [+ or -] 21.
Aspartate transaminase (AST), alanine transaminase (ALT), TNF-[alpha] (ELISA) and IL-6 levels (ELISA) were also determined in serum samples.
Patients on Alimta did experience higher rates of Grade 3 or 4 Alanine Transaminase (ALT), a laboratory measurement of liver function, compared to Taxotere.
Objectives: Up to 30% of the 5 million patients with chronic hepatitis C in the United States have normal serum alanine transaminase (ALT) levels.
Treatment responses--defined as undetectable HCV RNA and normalization of alanine transaminase after 24 weeks--were 17% and 24% in those on the 1- and the 1.
4 Serum creatinine (mmol/L) 70-120 228 77 Estimated glomerular >90 26 >90 filtration rate (mL/min) Albumin (g/L) 35-50 30 20 Globulin (g/L) 20-32 20 22 Total bilirubin ([micro]mol/L) 6-22 34 18 Alkaline phosphatase (IU/L) 33-125 970 746 Gamma glutamyl transferase 8-64 1796 1209 (IU/L) Alanine transaminase (IU/L) 8-37 46 53 Albumin corrected calcium 2.
At least one study has demonstrated that use of polyunsaturated fatty acids (PUFAs) by NASH patients improved their alanine transaminase (ALT) and triglyceride levels (Aliment.
05 mmol/l, alanine transaminase 418 U/l, gammaglutaryl transferase l 743 U/l, alkaline phosphatase 460 U/l, albumin 25 g/dl, haemoglobin 10.
Baseline alanine transaminase (ALT) was elevated in 2.
In the first blood results, troponin T-23 ng/ml, aspartate aminotransferase--139 U/L, alanine transaminase --76 U/L, lactate dehydrogenase--546 U/L, Urea--23 mg/dl, Creatinine--1.