alamethicin

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alamethicin

A peptide antibiotic and polyene ionophore which forms nonspecific potential gradient sensitive anion- or cation-transporting pores in plasma membranes or in artificial lipid membranes.

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For each substrate, we prepared at least eight different substrate concentrations in methanol (Table 1) and further diluted them in the reaction mixture to a final volume of 100 [micro]L, containing 50 mM phosphate buffer at pH 7.4, 10 mM magnesium chloride, the specific concentration of liver or intestinal microsomes (0.1 mg/mL for BPS, 0.05 mg/mL for BPF, and 0.01 mg/mL for BPAF), and alamethicin (5% of the total protein concentration).

Differences between human and rat intestinal and hepatic bisphenol A glucuronidation and the influence of alamethicin on in vitro kinetic measurements.

Physiologically Based Pharmacokinetic (PBPK) Modeling of the Bisphenols BPA, BPS, BPF, and BPAF with New Experimental Metabolic Parameters: Comparing the Pharmacokinetic Behavior of BPA with Its Substitutes

Trichoderma viride cellulase induces resistance to the antibiotic pore-forming peptide alamethicin associated with changes in the plasma membrane lipid composition of tobaccoBY-2 cells.

MANAGEMENT OF SCLEROTINIA WHITE ROT OF BEANS WITH ANTAGONISTIC MICROORGANISMS

Uridine diphosphate glucuronic acid (UDPGA), magnesium chloride (Mg[Cl.sub.2]), alamethicin, D-saccharic-1, and 4-lactone were provided from Sigma-Aldrich (St.

Briefly, the incubation mixture mainly contained 50 mM Tris-hydrochloric acid buffer (pH = 7.4), 0.88 mM Mg[Cl.sub.2], 22 [micro]g/mL alamethicin, 4.4 mM saccharolactone, and 3.5 mM UDPGA.

Metabolite Profiling, Pharmacokinetics, and In Vitro Glucuronidation of Icaritin in Rats by Ultra-Performance Liquid Chromatography Coupled with Mass Spectrometry

Uridine 5'diphosphate-glucuronic acid (UDPGA) trisodium salt and alamethicin were purchased from Sigma-Aldrich (St.

The incubation system consisted of 50 mM Tris-HCl buffer (pH 7.4), 0.25 mg/ml proteins (HLMs, HIMs, HKMs, or UGTs), 25 [micro]g/ml alamethicin, 8 mM Mg[Cl.sub.2], 1 mM UDPGA, and 5, 20, 50, or 200 [micro]M WEL in a total volume of 200 [mciro]l.

Wedelolactone metabolism in rats through regioselective glucuronidation catalyzed by uridine diphosphate-glucuronosyltransferases 1As (UGT1As)

coli--with a commercially available anti-Salmonella antibody and the antimicrobial peptide alamethicin. A Langmuir isotherm model was applied to determine the binding affinity constants of the peptides to the pathogens.

Microcantilevers rapidly detect pathogenic bacteria

Jelinek, "Microscopic visualization of alamethicin incorporation into model membrane monolayers," Langmuir, vol.

Penetration of milk-derived antimicrobial peptides into phospholipid monolayers as model biomembranes

An example for antimicrobial peptides that follows barrel-stave mechanisms includes alamethicin and gramicidin S [76-78].

Antimicrobial peptides: versatile biological properties

In summary, neither deoxycholate (a common detergent used in [Na.sup.+],[K.sup.+]-ATPase assays) nor alamethicin (a membrane-permeabilizing agent) had any effect on the total [Na.sup.+],[K.sup.+]-ATPase activity in homogenates of S.

Gene Expression and Enzyme Activities of the Sodium Pump During Sea Urchin Development: Implications for Indices of Physiological State

All major branches of chemistry were represented, covering topics from alamethicin to zeolites, from cyclodextrin to circular dichroism, and from the synthesis of Bao Gong Ten (by Vinh C.