deficiency or absence of the secretion of tears. It may be inherited as an autosomal dominant trait, or it may occur in association with other disorders or as an isolated congenital defect.
Deficiency of tear secretion.
[G. a- priv. + L. lacrima, tear]
Absence of secretion from the lacrimal gland. However, the typical picture is one of reduced tear secretion more correctly termed hypolacrima. It may occur as a result of occlusion of the orifices of the lacrimal gland due to trauma, cicatrization, diseases (e.g. trachoma); it may be congenital (e.g. Riley-Day syndrome) or it may be due to a neurogenic cause (secondary to brain damage) or to a systemic disease (e.g. Sjögren's syndrome). Treatment includes artificial tears, bland ointments, sealed scleral contact lenses and, in very severe cases, tarsorrhaphy. See keratoconjunctivitis sicca.