Mutational analysis of melanocortin-4 receptor, agouti-related protein, and alpha-melanocyte-stimulating hormone genes in severely obese children.
Plasma levels of agouti-related protein are increased in obese men.
Plasma agouti-related protein levels in women with anorexia nervosa.
Agouti-related protein in patients with acute and weight-restored anorexia nervosa.
Association between an agouti-related protein gene polymorphism and anorexia nervosa.
Deletion of agouti-related protein
blunts ethanol self-administration and binge-like drinking in mice.
Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein
(AGRP) has a central inhibitory action on the hypothalamic-pituitarythyroid (HPT) axis; comparisons between the effect of AGRP and neuropeptide Y on energy homeostasis and the HPT axis.
The melanocortin 4 receptor protein regulates the food intake process and body weight in cooperation with leptin and agouti-related protein
(AGRP), thus playing an important role in the maintenance of proper body weight (Dhillo et al., 2002; Switonski, 2013).
HMS is composed of two different populations of neurons, one set that expresses neuropeptides Y (NPY) and agouti-related protein
(AgRP) and a second set that expresses proopiomelanocortin (POMC), a precursor containing a-melanocyte-stimulating hormone (Richards et al., 2010).