The University of Birmingham is leading researchers as they investigate whether a GLP-1 agonist drug
, which is currently used to lower blood sugar in people with type II diabetes, could be repurposed to treat raised brain pressure, Pharma Times reported on Thursday.
PPARy agonist drug
Rosiglitazone was used (Sigma-Aldrich) and rosiglitazone inhibitor, GW-9662 (Sigma-Aldrich).
This study was carried out to investigate the anti-inflammatory activity of salbutamol, a [beta]2-adrenergic receptor agonist drug
, on acute (carrageenan-induced) and chronic (cotton pellet-induced) inflammation models.
Hauser found that PD patients who failed to obtain good symptom control after taking a certain dopamine agonist drug
, such as apomorphine (Apokyn), pramipexole (Mirapex), or ropinirole (Requip), achieved much greater symptom relief by taking the commonly prescribed PD drug rasagiline (Azilect).
Mark Robson, 56, became obsessed with gambling after taking the dopamine agonist drug
to control the symptoms of Parkinson's.
-- PharmaCare Specialty Pharmacy has been selected as a preferred provider of Apokyn, Bertek Pharmaceuticals Inc.'s dopamine agonist drug
indicated for the acute, intermittent treatment of so-called off episodes in patients suffering from motor complications associated with advanced Parkinson's disease.
Bremelanotide, which is a melanocortin 4 receptor agonist drug
candidate, is a synthetic peptide analog of the naturally occurring hormone alpha-MSH (melanocyte-stimulating hormone).
Competitive antagonism occurs where an agonist drug
or endogenous ligand is displaced from its receptors by an antagonist drug.
The variable affinity and efficacy of different agonist drugs
, and between different people, may be due to genetic variations in the structure, location and number of binding sites in the opioid receptors.
The class of GLP-1 agonist drugs
, meanwhile, reduced risk of death by 18%.
The lack of a "gold standard" medication treatment similar to what the agonist drugs
methadone and buprenorphine have become for opioid addiction clearly is creating much of the anxiety about any resurgence in stimulant dependence.