benign senescent forgetfulness

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benign senescent forgetfulness

A mild memory defect which is generally regarded as a normal ageing phenomenon, which falls along a continuum from banal and expected to frank dementia.
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TABLE Features of age-associated memory impairment vs mild cognitive impairment AGE-ASSOCIATED MILD COGNITIVE FEATURE MEMORY IMPAIRMENT IMPAIRMENT Clinical * [greater than or equal * Reported memory presentation to] 50 years of age complaint or memory with reported memory problems noted by an complaint (40% of informant people in their 50s * Learning and recall most and 85% of people >80 often affected years of age) * Normal mental status * Normal mental status * intact ADLs and subtle * Intact ADLs and IADLs changes in IADLs (such as managing finances) Memory test * Within 1 SD of the * More than 1.
Evidence that age-associated memory impairment is not a normal variant of aging.
5% demonstrated age-associated memory impairment, (7) and the incidence of the clinical diagnosis of mild cognitive impairment is as high as 24% in persons older than 65 years.
In 2004, the company completed two phase II safety trials of the drug for age-associated memory impairment and mild cognitive impairment, with a total 107 patients.