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HD is one of the most common causes of intestinal obstruction in newborn, being caused by the agangliosis of the bowel, from the internal anal sphincter to a variable distance proximally, most frequently affecting the rectosigmoid region.
Moreover, the clinical presentation can be directly influenced by the complications arising in HD's evolution, among which enterocolitis is considered to be multifactorial, mainly based on the connection between the agangliosis characterizing Hirschsprung disease, defective intestinal barrier and influence of altered commensal microflora [7, 8].
However, family's compliance regarding daily colon evacuation and also the presence of a rectosigmoid agangliosis, not of a pancolic involvement, contributed to a favorable evolution.