aganglionic


Also found in: Dictionary.
Related to aganglionic: intussusception, Aganglionic megacolon

aganglionic

 [a-gang″gle-on´ik]
lacking ganglion cells.

a·gan·gli·on·ic

(ā-gang-glē-on'ik),
Without ganglia.

aganglionic

(ā-găng′glē-ŏn′ĭk)
adj.
Lacking the presence of ganglia.

a·gan·gli·on·ic

(ā'gang-glē-on'ik)
Without ganglia.
References in periodicals archive ?
The main principle of surgery in Hirschsprung's disease is removal of the aganglionic segment and anastomosing a normal ganglionated segment which was first described by Swenson and Bill.
In HSCR, for example, obstructive physiology in the aganglionic segment is associated with upstream distension, inflammation, and smooth muscle hypertrophy, and could conceivably promote submucosal ganglion cell hyperplasia.
After H and E examination of slides, there were 36 (65%) cases proved to be Hirschsprung's disease (aganglionic) and 19 (34%) cases were nonHirschsprung's (ganglionic) group.
[sup][39] studied the bacteria of aganglionic colon in Ednrb−/− mice.
There is no problem in pediatric patients with Hirschsprung that aganglionic segment is located in colonic flexure while, the elderly patients may have limitations in this situation.
Given the favorable evolution of the acute episode and the patient's age and status, the surgical intervention was temporized, with assuring a proper prevention of complications and providing daily colon washout (Figure 2) at home until 8 months of age, when a laparoscopic assisted transanal pull-through (LATEP) with removal of the aganglionic colon segment and coloanal anastomosis using normally innervated colon was performed (Figures 3-6).
A lack of intestinal pacemaker (c-kit) in aganglionic bowel of patients with Hirschsprung's disease.
This bowel immaturity distinguishes it from Hirschsprung's disease, an aganglionic disorder of the distal bowel, which has the same clinical and radiographic findings (Diament, 2005).
If further testing is required, an unprepped barium enema is helpful for evaluating anatomy and may identify the aganglionic segment that is seen in Hirschsprung's disease.
An ex vivo gut explant assay showed mouse SKPs colonized and differentiated into [Ret.sup.k-/k-] aganglionic hindgut [62].
Only few PTHS patients have comorbidity for Hirschsprung's disease (HSCR) characterized by the absence of enteric ganglia along a variable bowel length (congenital aganglionic megacolon) [1].