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AFTER(1) Anistreplase Following Thrombolysis Effect on Reocclusion.
(2) Aspirin/Anticoagulant Following Thrombolysis with anistreplase (Eminase) in Recurrent Infarction. A trial comparing major acute cardiac events (MACE) rates in patients managed with aspirin or anticoagulation (anistreplase) post-thrombolysis for acute MI.
Primary endpoint 1 month, 3 month MACE
Conclusion No differences in MACE between aspirin and anistreplase; severe bleeding or stroke was greater with anistreplase.