Aflatoxin B1-DNA adduct | definition of aflatoxin B1-DNA adduct by Medical dictionary
aflatoxin B1-DNA adduct
aflatoxin B1-DNA adduct A molecular complex (adduct) formed by aflatoxin B1 attaching to DNA, which occurs in humans exposed to aflatoxins in mouldy peanuts or corn. ABDAs can be identified in the urine and liver by fluorescent microscopy, and are markers of aflatoxin exposure and indicate an increased risk for liver cancer (hepatocellular carcinoma).
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References in periodicals archive
Effects of vitamin C on the formation of aflatoxin B1-DNA adduct
in rat livers treated with radiation and aflatoxin B1.
By modulating cytochrome P450 function, curcumin reduces the aflatoxin B1-DNA adduct
formation, thereby showing its potential to inhibit chemical carcinogenesis .
XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts
and glycophorin A variant frequency.