A number of studies have shown a significant impact of climate fluctuation on the status of plants of each area and also on aeroallergens
and their public and clinical healths.
Sensitization in Childhood Asthmatics in North India.
Table I.- Comparison of aeroallergen
sensitized patients and Healthy controls (non-atopic) group for different parameters of the recruited persons.
sensitisation was tested using the ISAC test.
Skin prick-test reactivity to aeroallergens
and allergic symptoms in an urban population of central Italy: a longitudinal study.
In most children with AD, the development of asthma and AR is associated with sensitization to food allergens and/or aeroallergens
, while only a small percentage missed atopic diathesis.
A skin prick test was performed using an aeroallergen
kit that contained house dust mite, tree pollen, a mixture of herb-grain pollen, fungus, and animal epithelium-dander, and a food allergen kit containing milk and egg.
Geographical variation in the prevalence of positive skin tests to environmental aeroallergens
in the European Community Respiratory Health Survey I.
The intact respiratory mucosa has been established to contain no DCs at birth; however, the exposure to biologically active aeroallergens
(see Table 1) activates the respiratory epithelium.
Without these spatial-temporal details about the outdoor environment for the study population, it is difficult to empirically examine the impact of climate change on child asthma outcome, even though the hypotheses about these associated pathways (wild fires, change in aeroallergen
density, mold, insect population increase, etc.) are plausible.
Twenty-five subjects (50%) were sensitive to aeroallergen
, 15 to pollen of Japanese cedar (OR = 1.2; 95% CI: 0.5-2.8), and 10 to Japanese cypress (OR = 0.97; 95% CI: 0.4-2.6), while four (8%) had allergy for both food and inhalant allergens (OR = 1.3; 95% CI: 0.3-6.3).
As assessed by multivariate logistic regression analysis including age, history of wheezing, aeroallergen
, family history in the model, RV infection was independently associated with a higher risk of earlier wheezing episodes (OR, 3.441; 95% confidence interval [CI], 1.187-9.979; p = 0.023); eosinophilia and leukocytosis were more often observed in children with RV infection (OR, 11.584, 95% CI, 1.080-124.224; p = 0.043, OR, 1.188, 95% CI, 1.070-1.320; p = 0.001).