adult rickets


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os·te·o·ma·la·ci·a

(os'tē-ō-mă-lā'shē-ă),
A disease in adults characterized by a gradual softening and bending of the bones with varying severity of pain; softening occurs because the bones contain osteoid tissue that has failed to calcify because of lack of vitamin D or renal tubular dysfunction; more common in women than in men, osteomalacia often begins during pregnancy.
[osteo- + G. malakia, softness]

adult osteomalacia

A generic term for bone disease characterised by poor mineralisation, which overlaps with osteoporosis, but differs therefrom in that there is calcium deficiency due to low dietary calcium or lack of vitamin D, and phosphate deficiency due to renal loss.

Aetiology
Low intake of calcium and vitamin D or phosphorus, renal tubular acidosis, chronic renal failure, malnutrition, malabsorption, hypophosphataemia, anti-convulsant therapy, coeliac disease, cancer-related osteolysis.
 
Clinical findings
Begins with vague symmetrical pain, increased bone sensitivity, proximal muscle weakness, difficulty in climbing stairs.

Imaging
Pseudofractures.
 
Management
Pharmacologic doses of vitamin D.

os·te·o·ma·la·ci·a

(os'tē-ō-mă-lā'shē-ă)
A disease characterized by a gradual softening and bending of the bones with varying severity of pain; softening occurs because the bones contain osteoid tissue which has failed to calcify due to lack of vitamin D or renal tubular dysfunction.
Synonym(s): adult rickets, late rickets.
[osteo- + G. malakia, softness]

os·te·o·ma·la·ci·a

(os'tē-ō-mă-lā'shē-ă)
Disease in adults characterized by a gradual softening and bending of bones with varying severity of pain.
Synonym(s): adult rickets.
[osteo- + G. malakia, softness]
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