Adria Cell

Adria Cell

A term of art for a myocyte seen in patients with adriamycin cardiotoxicity, which is characterised by central clumping of the nuclear chromatin by electron microscopy and mild cytoplasmic vacuolization.
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The microscopic features characteristic of this diagnosis include a predominant finding of multifocal areas of patchy and interstitial fibrosis (stellate scars) and occasional vacuolated myocardial cells (Adria cells).[1] Myocyte hypertrophy and degeneration, loss of cross-striations, and absence of myocarditis are also characteristic of this diagnosis.