adrenomyeloneuropathy


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Related to adrenomyeloneuropathy: adrenoleukodystrophy

a·dre·no·my·e·lo·neu·rop·a·thy

(ă-drē'nō-mī'ĕ-lō-nū-rop'ă-thē),
A disorder of men, consisting of long-standing adrenal insufficiency, hypogonadism, progressive myelopathy, peripheral neuropathy, and sphincter disturbances; considered a variant of adrenoleukodystrophy.
[adreno- + G. myelos, medulla, + neuron, nerve, + pathos, suffering]

adrenomyeloneuropathy

/adre·no·my·elo·neu·rop·a·thy/ (-mi″ĕ-lo-ndbobr-rop´ah-the) a hereditary condition related to adrenoleukodystrophy but including spinal cord degeneration and peripheral neuropathy.

adrenomyeloneuropathy

An X-linked recessive disorder characterised by a non-inflammatory distal axonopathy involving mainly spinal cord, long tracts and to a lesser extent, peripheral nerves. It is a nervous system manifestation of adrenoleukodystrophy.

Clinical findings
Slowly progressive diplegia; peripheral neuropathy with or without primary adrenal failure, as well as primary testicular failure; red-green colour blindness; and depression. It affects 1 in 20–100,000 males, most commonly as cerebral adrenoleukodystrophy in childhood or adrenomyeloneuropathy in adulthood.

ad·re·no·my·e·lo·neu·rop·a·thy

(ă-drē'nō-mī'ĕ-lō-nūr-op'ă-thē)
A disorder of men, consisting of long-standing adrenal insufficiency, hypogonadism, progressive myelopathy, peripheral neuropathy, and sphincter disturbances; considered a variant of adrenoleukodystrophy.
[adreno- + G. myelos, medulla, + neuron, nerve, + pathos, suffering]
References in periodicals archive ?
Adrenomyeloneuropathy presenting as Addison's disease in childhood.