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Related to adrenocorticotropin: aldosterone, emedullate, hypomastia


1. a hormone secreted by the anterior lobe of the pituitary gland that stimulates the cortex of the adrenal gland to secrete its hormones, including corticosterone. If production of corticotropin falls below normal, the adrenal cortex decreases in size, and production of the cortical hormones declines.
2. a pharmaceutical preparation of animal-derived corticotropin, administered intravenously for diagnostic testing of adrenocortical function and subcutaneously or intramuscularly, in a slowly absorbed gel form (repository corticotropin), as an anticonvulsant for treating infantile spasms. Called also adrenocorticotropic hormone (ACTH), adrenocorticotropin, and corticotrophin.

a·dre·no·cor·ti·co·tro·pic hor·mone (ACTH),

the hormone of the anterior lobe of the hypophysis that governs the nutrition and growth of the adrenal cortex, stimulates it to functional activity, and shows extraadrenal adipokinetic activity; it is a polypeptide containing 39 amino acids, but exact structure varies from one species to another; sometimes prefixed by α to distinguish it from β-corticotropin. The first 13 amino acids at the N-terminal region are identical to α-melanotropin.


/adre·no·cor·ti·co·trop·in/ (-kor″tĭ-ko-tro´pin) corticotropin.


(ə-drē′nō-kôr′tĭ-kō-trŏp′ĭn, -trō′pĭn) also


(-trŏf′ĭn, trō′fĭn)


the adrenocorticotropic hormone secreted by the adenophyophysis that stimulates secretion of corticosteroid hormones by the adrenal cortex.


A gene on chromosome 2p23 that encodes proopiomelanocortin, the melanocortin family of hormones, which include alpha-, beta- and gamma-melanocyte stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). The melanocortins bind to the melanocortin receptors, a group of five G protein-coupled receptors (MC1R to MC5R) which are involved in a wide range of physiological functions, including pigmentation, energy homeostasis, inflammation, immunomodulation, steroidogenesis and temperature control.

Molecular pathology
Defects of POMC are associated with susceptibility to obesity and proopiomelanocortin deficiency.


Protein hormone of the anterior pituitary gland that stimulates the cortex of the suprarenal gland.

Adrenocorticotropin (corticotrophin)

A hormone that acts on cells of the adrenal cortex, causing them to produce male sex hormones and hormones that control water and mineral balance in the body.
Mentioned in: Pituitary Dwarfism

adrenocorticotropin (ədrē´nōkôr´-tikōtrō´pin),

n See ACTH.


adrenocorticotropic hormone (acth) or corticotropin.
References in periodicals archive ?
Blood levels of adrenocorticotropin and another hormone, cortisol, increased as the night progressed.
Hypothalamic monoaminergic control of stress induced adrenocorticotropin release in a rat.
The pituitary gland releases another hormone, called ACTH, for adrenocorticotropin hormone.
adrenocorticotropin (ACTH)--stimulates the adrenal glands to produce cortisol;
Drugs such as Adrenocorticotropin Hormone (ACTH), vigabatrin, prednisone, pyridoxine and valproate are commonly prescribed for the treatment of infantile spasms.
These neurons secrete CRF and the hormone vasopressin into the portal circulation, which then triggers the release of adrenocorticotropin hormone (ACTH) from the anterior pituitary gland.
Secondary AI occurs when the pituitary gland fails to produce enough adrenocorticotropin (ACTH), a hormone that stimulates the adrenal glands to produce cortisol.
Cortisolemic indices predict severe infections in Cushing syndrome due to ectopic production of adrenocorticotropin.
1983) Plasma adrenocorticotropin and cortisol responses to submaximal and exhaustive exercise.
Ectopic adrenocorticotropin production: disappearance after removal of inflammatory tissue.
Altered adrenocorticotropin and Cortisol secretion in abdominal obesity: implications for the insulin resistance syndrome.

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