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1. a hormone secreted by the anterior lobe of the pituitary gland that stimulates the cortex of the adrenal gland to secrete its hormones, including corticosterone. If production of corticotropin falls below normal, the adrenal cortex decreases in size, and production of the cortical hormones declines.
2. a pharmaceutical preparation of animal-derived corticotropin, administered intravenously for diagnostic testing of adrenocortical function and subcutaneously or intramuscularly, in a slowly absorbed gel form (repository corticotropin), as an anticonvulsant for treating infantile spasms. Called also adrenocorticotropic hormone (ACTH), adrenocorticotropin, and corticotrophin.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
In conditions such as Cushing's disease or ectopic adrenocorticotrophin production where GC levels in the plasma are high, the 11[beta]-HSD2 is thought have reached saturation kinetics as opposed to impairment.
Androgen regulation of adrenocorticotrophin and corticosterone secretion in the male following novelty and foot shock stress.
After review of MP's psychomotor development--slowed because of the persistent seizures--and discussion of potential side effects, the decision was made to treat MP with the pituitary hormone ACTH (adrenocorticotrophin).
Differential androgen response to adrenocorticotrophin hormone stimulation and effect of opioid antagonist on insulin secretion in polycystic ovarian syndrome.
Glucocorticoids, stimulated by adrenocorticotrophin (ACTH) that is secreted from the pituitary gland upon the initiation of stressful events, have diverse suppressive effects on the immune system.
Relationships among plasma cortisol, adrenocorticotrophin, and severity of injury in recently injured patients.

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